Raman Spectroscopy Training Workshop

Metrohm UK

21st July

Event

Metrohm UK

£450 per person for full day or £250 per person for half day (includes lunch and refreshments)

NanoRam Training Agenda (9:30 am – 12:30 pm)

Raman spectroscopy theory

Raman effect fundamentals, spectral fingerprints & vibrational interpretation essentials, signal quality factors

Regulatory & compliance

GMP/PIC/S requirements for handheld Raman, expectations for raw material identification, understanding p-value / HQI-based decision criteria, compliance documentation & audit trails

NanoRam instrument overview

Hardware components & optical design, calibration, verification & performance checks, system capabilities and limitations

Sampling & adaptor selection

Attachments, spectral interpretation basics, managing fluorescence and poor-quality spectra, real-world sampling tips

Software & method development

Library creation & management, identification vs investigation modes, method optimisation: thresholds, presets, specificity, data management

Hands-on practical session

Running standard ID tests, investigation mode for unknowns, reviewing HQI/p-value results, troubleshooting user-level issues

Mira P Training Agenda (1:00 pm – 4:30 pm)

Raman spectroscopy fundamentals

Raman scattering principles, spectra as molecular fingerprints, key factors affecting signal quality (fluorescence, SNR, optics)

Instrument overview

Hardware components (laser, sampling optics, spectrograph, detector), attachments & adaptors, calibration & verification overview (ASTM E1840, polystyrene)

Sampling techniques & best practices

Avoiding fluorescence issues, ensuring consistent sampling, Interpreting live spectra and quality metrics, choosing the correct adaptor for solids, liquids, packaging

MiraCal P software training

Connecting Mira P to MiraCal, managing users & permissions, building & editing, using Model Expert to validate training spectra, data management

Hands-on practical workshop

Running Identification mode, running investigation mode, reviewing match results (p-value, spectral overlay), understanding spectral variance, troubleshooting common issues (fluorescence, noisy spectra, poor contact)

Performance verification & compliance

Method development considerations, avoiding false positives/false negatives, documenting verification steps, regulatory expectations (GMP, PIC/S)

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