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Industries (1)Coulometric Karl Fischer titrators
Stand-alone or computer-controlled coulometers for the determination of low water content or moisture content (0.001 to 1%) by coulometric titration.
OMNIS KF titrators
Fully integrated solution for water content determination with volumetric and coulometric Karl Fischer titration.
Eco KF Titrator
High in quality, low in price: Swiss-made, affordable solution for routine volumetric Karl Fischer titration.
KF Ti-Touch
Compact all-in-one volumetric or coulometric Karl Fischer titrator for routine water content determination.
KF Titrando
Volumetric and coulometric Karl Fischer titrator for accurate determination of any water content, from 0.001 to 100%.
OMNIS titrators
All-in-one potentiometric autotitrator platform: faster results, safer handling of chemicals, and maximum modularity for easier adaptability to your requirements.
Sample preparation for KF Ti-Touch
Reliable solutions when the water content of samples cannot be titrated directly.
Sample preparation for KF Titrando coulometers
Solutions for sample preparation with KF Titrando coulometers when samples cannot be titrated directly.
2.1001.4220
OMNIS Titrator KFThe OMNIS Titrator KF offers you the complete package for volumetric Karl Fischer titration. Included in the package is the OMNIS Basic Titrator with magnetic stirrer for potentiometric end point titration, the function license for KFT with conditioning, the OMNIS Solvent Module and the complete accessories for volumetric Karl Fischer titration.Benefit from the unique user-friendliness of an automatic start of titration after sample addition and maximum safety thanks to contact-free reagent handling with the 3S-Liquid Adapter and OMNIS Solvent Module.
2.860.0010
860 KF ThermoprepThe 860 KF Thermoprep is designed for thermal sample preparation in Karl Fischer titration.Numerous substances cannot be analysed by direct Karl Fischer titration as they are not soluble, react with the Karl Fischer reagent or release their water only very slowly or not until heated to high temperatures. Using tightly sealed sample vials, the sample is inserted in the oven. The samples can be subsequently analysed by any volumetric or coulometric KF titrator.
2.901.0010
901 TitrandoThe Karl Fischer Titrando for the modern titration laboratoryIn addition to the Karl Fischer mode (KFT), the high-end titrator is also equipped with the SET mode and can thus perform titrations to a predefined endpoint."iTrode ready": As a result of the high-resolution, galvanic measuring interface – now also for the first time with additional digital measuring input for the intelligent "iTrodes" electrodes – it is additionally possible to perform pH measurements with a maximum of precision.Thanks to the four MSB connectors, up to four Dosinos can be connected to the 901 Titrando. These can be used not only for titration, but also for the automated addition of sample, standard and auxiliary solutions such as solubility promoters. Furthermore, you have all of the Liquid Handling commands at your disposal, which means that the aspiration of exhausted reagent and the addition of fresh solvent can also be automated.For use with OMNIS Software, tiamo software, or Touch Control unit. Compliance with GMP/GLP and FDA regulations such as 21 CFR Part 11, if required
2.890.0110
890 Titrando with Touch ControlThe 890 Titrando is a high-end titrator for volumetric Karl Fischer titrations. The instrument is equipped with a built-in buret drive, four MSB connectors, a galvanically separated measuring interface and a USB connector. The Touch Control operating unit with touch-sensitive screen for controlling the Titrando, the 803 Ti Stand and a 10 mL exchange unit are included in the scope of delivery.
2.874.0120
874 Oven Sample ProcessorThe 874 Oven Sample Processor is used for automatic thermal sample preparation in Karl Fischer titration. The oven method is particularly suitable for samples that do not release their water until higher temperatures have been reached, for sparingly soluble samples, or those that react with the KF reagent.
2.874.0130
874 Oven Sample Processor special vialsThe 874 Oven Sample Processor is used for automatic thermal sample preparation in Karl Fischer titration. The oven method is particularly suitable for samples that do not release their water until higher temperatures have been reached, for sparingly soluble samples, or those that react with the KF reagent.This instrument can be modified to match customer-specific sample vessels. Please contact your Metrohm representative for further information.
2.875.9050
875 KF Gas Analyzer without monitorThe 875 KF Gas Analyzer is a completely configured analysis system. The instrument contains a computer with tiamo™ full titration software installed in addition to an 851 Titrando for automatic coulometric water content determination. Predefined methods for water content determination in liquefied and permanent gases facilitate work with the 875 KF Gas Analyzer.In addition to determining water content in gases, the system can also be used for determining water content in liquid and solid samples.Complies entirely with the requirements of the standard: ASTM D7995 - 19: Standard Test Method for Total Water in Liquid Butane by Liquefied Gas Sampler and Coulometric Karl Fischer Titration
2.1018.0010
OMNIS Coulometer without stirrerOMNIS Coulometer without magnetic stirrer for stand-alone operation or as the heart of an OMNIS titration system. The coulometer can be enhanced with additional titration, dosing or coulometer modules.Coulometry is the ideal method for water content determination in the trace range (10 μg to 10 mg absolute water content) in liquids, solids and gases. In addition, coulometric Karl Fischer titration is an absolute method making titer determination unnecessary.
2.1018.0020
OMNIS Coulometer with stirrerOMNIS Coulometer with magnetic stirrer for stand-alone operation or as the heart of an OMNIS titration system. The coulometer can be enhanced with additional titration, dosing or coulometer modules.Coulometry is the ideal method for water content determination in the trace range (10 μg to 10 mg absolute water content) in liquids, solids and gases. In addition, coulometric Karl Fischer titration is an absolute method making titer determination unnecessary.
2.915.0110
915 KF Ti-Touch"Reduce to the max" – that is the concept behind the 915 KF Ti-Touch. The new compact titrator for Karl Fischer titration from Metrohm offers the maximum in the class of stand-alone systems for routine analysis.Burets, stirrer, dosing unit and Touch Control are integrated in a single, compact system unit. This saves a great deal of space on the laboratory table.The 915 KF Ti-Touch now also fulfills FDA Regulation 21 CFR, Part 11. This means you are always on the safe side when it comes to audits.The package includes the 915 KF Ti-Touch, an 800 Dosino, a 10 mL dosing unit and additional accessories.
MATi 10
Automated volumetric KF titrationsFully automated system for volumetric Karl Fischer water content determination in up to 24 samples. The system is controlled with OMNIS software and consists of an 814 USB Sample Processor, a 901 Titrando and extensive accessories.The samples are weighed out into the beakers, sealed to protect against humidity and placed on the rack. Before the actual titration, they are dissolved in a defined volume of KF working medium, after which the water content is titrated.This method is particularly suitable for samples that dissolve readily in the KF working medium. In addition, solubility can be improved by using suitable solubility promoters.
MATi-11
Automated volumetric KF titration including sample preparationFully automated system for volumetric Karl Fischer water content determination in up to 53 samples. This system is controlled with OMNIS software and consists of an 815 Robotic USB Sample Processor XL, a 901 Titrando, a Polytron PT 1300 D and extensive accessories.The samples are weighed out into beakers, sealed to protect against humidity and placed on the rack. Before the actual titration, a defined volume of KF reagent is added and the sample is pulverized with the help of a Polytron. The water that is released is titrated afterwards. Even samples of poor solubility, e.g., tablets, can be analyzed without difficulty with this method. The use of solubility promoters can be avoided in this way.
2.917.0010
917 Coulometer with generator electrode with diaphragmThe 917 Coulometer is a compact titrator for coulometric water determination in accordance with Karl Fischer. ''Reduced to the max'' – operating module, stirrer and pump are integrated in the 917 Coulometer for rapid reagent replacement. This saves a great deal of space on the laboratory table.Recommended measuring range: 10 µg…200 mg absolute waterCoulometry is the ideal method for water content determination in liquids, solids and gases in the trace range. In addition, coulometry is an absolute method and thus no titer determination is necessary.The 917 Coulometer now also fulfills FDA Regulation 21 CFR, Part 11. This means you are always on the safe side when it comes to audits.
2.917.0110
917 Coulometer with generator electrode without diaphragmThe 917 Coulometer is a compact titrator for coulometric water determination in accordance with Karl Fischer. ''Reduced to the max'' – operating module, stirrer and pump are integrated in the 917 Coulometer for rapid reagent replacement. This saves a great deal of space on the laboratory table.Recommended measuring range: 10 µg…200 mg absolute waterCoulometry is the ideal method for water content determination in liquids, solids and gases in the trace range. In addition, coulometry is an absolute method and thus no titer determination is necessary.The 917 Coulometer now also fulfills FDA Regulation 21 CFR, Part 11. This means you are always on the safe side when it comes to audits.
2.852.0150
852 Titrando with generator electrode without diaphragmCoulometer including generator electrode without diaphragm and complete volumetric titration cellCoulometry is the ideal method for water content determination in liquids, solids, and gases when it comes to water content determination in the trace range (10 µg to 10 mg absolute water). In addition, coulometry is an absolute method and thus no titer determination is necessary.Recommended coulometry measuring range: 10 µg - 200 mg absolute water.The 852 Titrando controls not only coulometric, but also volumetric Karl Fischer titration.For use with OMNIS Software, tiamo software, or Touch Control unit. Compliance with GMP/GLP and FDA regulations such as 21 CFR Part 11, if required.
2.852.0050
852 Titrando with generator electrode with diaphragmCoulometer including generator electrode with diaphragm, 801 Magnetic Stirrer, and complete volumetric titration cell.Coulometry is the ideal method for water content determination in liquids, solids, and gases when it comes to water content determination in the trace range (10 µg to 10 mg absolute water). In addition, coulometry is an absolute method and thus no titer determination is necessary.Recommended coulometry measuring range: 10 µg - 200 mg absolute waterThe 852 Titrando controls not only coulometric, but also volumetric Karl Fischer titration.For use with OMNIS Software, tiamo software, or Touch Control unit. Compliance with GMP/GLP and FDA regulations such as 21 CFR Part 11, if required.
2.760.0020
Sample changer KFT 760Complete system for automatic volumetric Karl Fischer titration.
2.906.0010
906 TitrandoHigh-end titrator for potentiometric and volumetric Karl Fischer titration with one measuring interface and internal buret drive. built-in buret drive; dynamic (DET), monotonic (MET) and endpoint titration (SET), enzymatic and pH-STAT titrations (STAT), Karl Fischer titration (KFT); Measurement with ion-selective electrodes (MEAS CONC); "iTrode" intelligent electrodes; Dosing functions with monitoring, liquid handling; four MSB connectors for additional stirrers or dosing device systems; USB connector; For use with OMNIS Software, tiamo software, or Touch Control; Complies with GMP/GLP and FDA regulations such as 21 CFR Part 11, if required;
2.906.0020
906 TitrandoHigh-end titrator for potentiometric and volumetric Karl Fischer titration with 2 measuring interfaces and internal dosing drive. built-in dosing drive; dynamic (DET), monotonic (MET) and endpoint titration (SET), enzymatic and pH-STAT titrations (STAT), Karl Fischer titration (KFT); Measurement with ion-selective electrodes (MEAS CONC); Dosing functions with monitoring, liquid handling; 4 MSB connectors; 2 galvanically isolated measuring interfaces; USB connector; For use with OMNIS Software, tiamo software, or Touch Control; Complies with GMP/GLP and FDA regulations such as 21 CFR Part 11, if required;
2.907.0010
907 TitrandoHigh-end titrator for potentiometric and volumetric Karl Fischer titration with one measuring interface and Dosino dosing units. up to four dosing device systems of the 800 Dosino type; dynamic (DET), monotonic (MET) and endpoint titration (SET), enzymatic and pH-STAT titrations (STAT), Karl Fischer titration (KFT); Measurement with ion-selective electrodes (MEAS CONC); "iTrode" intelligent electrodes; Dosing functions with monitoring, liquid handling; four MSB connectors for additional stirrers or dosing device systems; USB connector; For use with OMNIS Software, tiamo software, or Touch Control; Complies with GMP/GLP and FDA regulations such as 21 CFR Part 11, if required;
2.907.0020
907 TitrandoHigh-end titrator for potentiometric and volumetric Karl Fischer titration with two measuring interfaces and Dosino dosing units. up to four dosing device systems of the 800 Dosino type; dynamic (DET), monotonic (MET) and endpoint titration (SET), enzymatic and pH-STAT titrations (STAT), Karl Fischer titration (KFT); "iTrode" intelligent electrodes; Measurement with ion-selective electrodes (MEAS CONC); Dosing functions with monitoring, liquid handling; four MSB connectors for additional stirrers or dosing device systems; USB connector; For use with OMNIS Software, tiamo software, or Touch Control; Complies with GMP/GLP and FDA regulations such as 21 CFR Part 11, if required;
2.803.0010
803 TI Stand with stirrer and pumpCompact titration stand with magnetic stirrer and built-in pump for solvent addition and aspiration of the titration vessel contents. Suitable for Karl Fischer titrations with Titrandos. MSB connection.Including comprehensive accessories, solvent bottle and waste bottle.
2.917.1010
917 Coulometer with generator electrode with diaphragm and 860 KF ThermoprepThe 917 Coulometer is a compact titrator for coulometric water determination in accordance with Karl Fischer. ''Reduced to the max'' – operating module, stirrer, and pump are integrated in the 917 Coulometer for rapid reagent replacement. This saves a great deal of space on the laboratory table.The 917 Coulometer now also fulfills FDA Regulation 21 CFR, Part 11. This means you are always on the safe side when it comes to audits.The 860 KF Thermoprep is used for thermal sample preparation. Many substances are not suitable for direct Karl Fischer titration because they are not soluble, react with the KF reagent, or because they only release their water content very slowly or only at high temperatures. Each of the samples is introduced into the oven in tightly sealed sample vessels and their water content is determined with the 917 Coulometer.
2.917.1110
917 Coulometer with generator electrode without diaphragm and 860 KF ThermoprepThe 917 Coulometer is a compact titrator for coulometric water determination in accordance with Karl Fischer. ''Reduced to the max'' – operating module, stirrer and pump are integrated in the 917 Coulometer for rapid reagent replacement. This saves a great deal of space on the laboratory table.The 917 Coulometer now also fulfills FDA Regulation 21 CFR, Part 11. This means you are always on the safe side when it comes to audits.The 860 KF Thermoprep is used for thermal sample preparation. Many substances are not suitable for direct Karl Fischer titration because they are not soluble, react with the KF reagent or because they release their water content only very slowly or only at high temperatures. Each of the samples is introduced into the oven in tightly sealed sample vessels and their water content is determined with the 917 Coulometer.
2.890.0010
890 TitrandoHigh-end titrator with built-in buret drive for volumetric Karl Fischer titrations.With four MSB connections, one galvanically isolated measuring interface and USB connector.Operation with 900 Touch Control or OMNIS SoftwareWith KF titration vessel und double Pt ring electrode for KFT, without 803 Ti-Stand and exchange unit.
2.888.0010
888 TitrandoHigh-end titrator with built-in buret driveWithout accessories; Operation with 900 Touch Control or OMNIS Software; Dynamic (DET), monotonic (MET), endpoint titration (SET), and Karl Fischer titration (KFT, only with operation with OMNIS SW); Four MSB connectors; one galvanically isolated measuring interface (also for intelligent "iTrodes" electrodes); USB connector;
2.756.0010
756 KF Coulometer with generator electrode with diaphragmKF coulometer with built-in printer and titration cell with generator electrode with diaphragm for water content determination down to trace levels.This coulometer has become indispensable in many laboratories thanks to its reliability, its backlit graphical display, the multi-language dialog and the simplicity of its operation. The clear display provides information regarding the relevant titration parameters and unambiguous indication of the progress of the titration in the form of a curve showing µg water over time.Recommended measuring range: 10 µg - 200 mg absolute water
2.756.0110
756 KF Coulometer with generator electrode without diaphragmKF coulometer with built-in printer and titration cell with generator electrode without diaphragm for water content determination down to trace levels.This coulometer has become indispensable in many laboratories thanks to its reliability, its backlit graphical display, the multi-language dialog and the simplicity of its operation. The clear display provides information regarding the relevant titration parameters and unambiguous indication of the progress of the titration in the form of a curve showing µg water over time.Recommended measuring range: 10 µg - 200 mg absolute water
2.831.0010
831 KF Coulometer with generator electrode with diaphragmInexpensive coulometer including titration cell and generator electrode with diaphragm for water content determination down to trace levels.This coulometer has become indispensable in many laboratories, thanks to its reliability, its backlit graphical display, the multi-language dialog and the simplicity of its operation. The clear display provides information regarding the relevant titration parameters and unambiguous indication of the progress of the titration in the form of a curve showing µg water over time.Recommended measuring range: 10 µg - 200 mg absolute water
2.831.0110
831 KF Coulometer with generator electrode without diaphragmInexpensive coulometer including titration cell with generator electrode without diaphragm for water content determination down to the trace range.This coulometer has become indispensable in many laboratories, thanks to its reliability, its backlit graphical display, the multi-language dialog and the simplicity of its operation. The clear display provides information regarding the relevant titration parameters and unambiguous indication of the progress of the titration in the form of a curve showing µg water over time.Recommended measuring range: 10 µg - 200 mg absolute water
2.824.0020
824 Easy Sample ChangerThe economic sample changer for routine use.Easy Sample Changer Micro: sample changer for titrations with smaller sample volumes. Up to 24 samples with a maximum volume of 75 mL can be processed in a single run. With the KFT equipment the Easy Sample Changer can be converted to a Karl Fischer sample changer.
2.885.0010
885 Compact Oven Sample ChangerThe 885 Compact Oven Sample Changer is used for thermal sample preparation in Karl Fischer titration. In the oven the samples can be heated up to 250°C. The moisture contained in the sample evaporates and is transported by a dry carrier gas into the titration cell, where the analysis takes place.
2.1027.0010
Eco KF TitratorThe new Eco KF Titrator with integrated magnetic stirrer und touch-sensitive display is ideal for routine water content determination. Predefined methods enable a smooth and easy instrument start-up. In addition to GLP-compliant printouts on paper or as PDFs, the Eco KF Titrator also offers the option of connecting balances or of sending the determination data to a PC via PC / LIMS reports.
2.1029.0010
Solvent PumpSolvent Pump is used with an Eco Titrator / Eco KF Titrator / Eco Coulometer for reliably adding solvent and aspirating off titration vessel content without contact with the reagents.Device-independent use is also possible with optional 6.2164.010 power supply unit.
2.870.0010
870 KF Titrino plusThe inexpensive 870 KF Titrino plus is a KF titrator for volumetric water content determination. With it, water contents from a few ppm to 100% can be determined reliably and precisely in solid, liquid and gaseous samples.With its user interface, which is tailored to routine users, the 870 KF Titrino plus is so simple to operate that only brief orientation periods are required. It is the ideal titrator for routine determinations, also because of its robustness.Titration vessel and electrode are included in the scope of delivery.
2.899.0010
899 Coulometer with generator electrode with diaphragmThanks to the integrated stirrer, the 899 Coulometer takes up less space on the laboratory table than a sheet of DIN A4 paper. Although small and compact, the coulometer does not compromise on performance. Water contents can be determined with precision down to trace levels. Indicator electrode and generator electrode with diaphragm are included in the scope of delivery.Recommended measuring range: 10 µg - 200 mg absolute waterCoulometry is the ideal method for water content determination in liquids, solids and gases in the trace range. In addition, coulometry is an absolute method and thus no titer determination is necessary.
2.899.0110
899 Coulometer with generator electrode without diaphragmThanks to the integrated stirrer, the 899 Coulometer takes up less space on the laboratory table than a sheet of DIN A4 paper. Although small and compact, the coulometer does not compromise on performance. Water contents can be determined with precision down to trace levels. Indicator electrode and generator electrode without diaphragm are included in the scope of delivery.Recommended measuring range: 10 µg - 200 mg absolute waterCoulometry is the ideal method for water content determination in liquids, solids and gases in the trace range. In addition, coulometry is an absolute method and thus no titer determination is necessary.
2.888.0310
888 Titrando with OMNIS SWHigh-end titrator with built-in buret drive• Includes OMNIS standalone license, 801 Stirrer magnetic stirrer, 20 mL exchange unit and combined "Ecotrode plus" pH glass electrode• Dynamic (DET), monotone (MET), end point titration (SET), Karl-Fischer Titration (KFT)• Four MSB connectors• Optional second buret for titration• A galvanically isolated measuring interface (also for intelligent electrodes "iTrodes")• USB connector
2.890.0310
KF Titrando with OMNIS SWThe 890 Titrando is a high-end titrator for volumetric Karl Fischer titrations. The instrument is equipped with a built-in buret drive, four MSB connectors, a galvanically separated measuring interface, and a USB connector. The OMNIS titration software for controlling the Titrando, the 803 Ti Stand and a 10 mL exchange unit are included in the scope of delivery
2.1027.0100
Eco KF Titrator assemblyThe new Eco KF Titrator with integrated magnetic stirrer and touch-sensitive display is ideal for routine water content determination. Predefined methods enable a smooth and easy instrument start-up. In addition to GLP-compliant printouts on paper or as PDFs, the Eco KF Titrator also offers the option of connecting balances or of sending the determination data to a PC via PC / LIMS reports.Complete package including Solvent Pump for rapid reagent replacement without chemical contact.
2.1028.0010
Eco Coulometer with generator electrode with diaphragmThe Eco Coulometer with integrated magnetic stirrer and touch-sensitive display is ideal for water content determination in the 10 µg to 200 mg absolute water range. Predefined methods enable a smooth and easy instrument start-up. In addition to GLP-compliant printouts on paper or as PDFs, the Eco Coulometer also offers the option of being able to connect balances or send determination data to a PC via PC / LIMS reports. Indicator electrode and generator electrode with diaphragm are included in the scope of delivery.Coulometry is the ideal method for water content determination in the trace range in liquids, solids and gases. In addition, coulometry is an absolute method making titer determination unnecessary.
2.1028.0110
Eco Coulometer with generator electrode without diaphragmThe Eco Coulometer with integrated magnetic stirrer and touch-sensitive display is ideal for water content determination in the 10 µg to 200 mg absolute water range. Predefined methods enable a smooth and easy instrument start-up. In addition to GLP-compliant printouts on paper or as PDFs, the Eco Coulometer also offers the option of being able to connect balances or send determination data to a PC via PC / LIMS reports. Indicator electrode and generator electrode without diaphragm are included in the scope of delivery.Coulometry is the ideal method for water content determination in the trace range in liquids, solids and gases. In addition, coulometry is an absolute method making titer determination unnecessary.
2.1030.1020
OMNIS Sample Robot Oven 2 x 6 mLOMNIS Sample Robot Oven with 2 oven modules 6 mL and extensive accessories for the direct transition to fully automated thermal sample preparation with subsequent water determination in accordance with Karl Fischer. The system provides space in 2 sample racks for 100 sample beakers of 6 mL each. This modular system is supplied completely installed and can thus be put into operation in a very short time.
ZBADI20162
Titrolyzer ADI2016 KF SS316The ADI 2016 Titrolyzer performs Volumetric Karl Fischer moisture/water determinations over a wide measurement range. Online closed loop sampling eliminates atmospheric moisture contamination when samples are taken manually and transported to the laboratory. Each step in analyzing the water content remains fixed and the same resulting in high repeatability. The analyzer is suitable for low ppm to percentage ranges of water content and equipped with all the features needed for 24/7 operation.
2.1001.0010
OMNIS Titrator without stirrer, without function licenseInnovative, modular potentiometric OMNIS Titrator. Thanks to 3S Liquid Adapter technology, handling chemicals is safer than ever before. The titrator can be freely configured with measuring modules and cylinder units and can have a stirrer added as needed. Thanks to various software function licenses, various measuring modes and functionalities are possible. Actuation via PC or local network; Connection option for up to four additional titration or dosing modules for additional applications or auxiliary solutions; Can be supplemented with magnetic stirrer and/or rod stirrer; Various cylinder sizes available: 5, 10, 20 or 50 mL; Liquid Adapter with 3S technology: Safe handling of chemicals and automatic transfer of the reagent dataMeasuring modes and software options:; Endpoint titration: "Basic" function license; Endpoint and equivalence point titration (monotonic/dynamic): "Advanced" function license; Endpoint and equivalence point titration (monotonic/dynamic) with parallel titration: "Professional" function license; Optional licenses for additional measuring, titration, and operating modes (e.g. volumetric Karl Fischer titration, conductometric or thermometric titration, coulometry, determination of the bromine index);
2.831.2110
831 KF Coulometer and 860 KF ThermoprepThis titration system is comprised of an 831 Coulometer and an 860 KF Thermoprep.This means that samples unsuitable for direct Karl Fischer titration can be analyzed. With the aid of tightly sealed sample vials, the samples are moved into the oven of the 860 KF Thermoprep. The sample is heated up, the water it contains is vaporized and channeled into the titration cell. The water content of the sample is then determined with the 831 Coulometer.
2.899.2110
899 Coulometer with generator electrode without diaphragm and 860 KF ThermoprepThis titration system is comprised of an 899 Coulometer and an 860 KF Thermoprep.This means that samples unsuitable for direct Karl Fischer titration can be analyzed. With the aid of tightly sealed sample vials, the samples are moved into the oven of the 860 KF Thermoprep. The sample is heated up, the water it contains is vaporized and channeled into the titration cell. The water content of the sample is then determined with the 899 Coulometer.
MATi 04
Automated coulometric KF titrationsMATi 4 is a fully automated system for coulometric KF titrations with high sample throughput. Up to 160 samples in 6 mL vials can be placed on the sample rack of the Sample Processor. The sample is pipetted into an external coulometric cell and then titrated there. The system is controlled with the OMNIS software.
2.831.2010
831 KF Coulometer and 860 KF ThermoprepThis titration system is comprised of an 831 Coulometer (with generator electrode with diaphragm) and an 860 KF Thermoprep.This means that samples unsuitable for direct Karl Fischer titration can be analyzed. With the aid of tightly sealed sample vials, the samples are moved into the oven of the 860 KF Thermoprep. The sample is heated up, the water it contains is vaporized and channeled into the titration cell. The water content of the sample is then determined with the 831 Coulometer.
2.870.2010
870 KF Titrino plus and 860 KF ThermoprepThis titration system is comprised of an 870 KF Titrino plus and an 860 KF Thermoprep. This means that samples unsuitable for direct Karl Fischer titration can be analyzed. With the aid of tightly sealed sample vials, the samples are moved into the oven of the 860 KF Thermoprep. The sample is heated up, the water it contains is vaporized and channeled into the titration cell. The water content of the sample is then determined with the 870 KF Titrino plus.
2.1030.1010
OMNIS Sample Robot Oven 1 x 6 mLOMNIS Sample Robot Oven with 1 oven module 6 mL and extensive accessories for the direct transition to fully automated thermal sample preparation with subsequent water determination in accordance with Karl Fischer. The system provides space in 2 sample racks for 100 sample beakers of 6 mL each. This modular system is supplied completely installed and can thus be put into operation in a very short time. The system can also be extended upon request to include an additional oven module, thus doubling the throughput.
2.1030.1030
OMNIS Sample Robot Oven 1 x 8 mLOMNIS Sample Robot Oven with 1 oven module 8 mL and extensive accessories for the direct transition to fully automated thermal sample preparation with subsequent water determination in accordance with Karl Fischer. The system provides space in 2 sample racks for 100 sample beakers of 8 mL each. This modular system is supplied completely installed and can thus be put into operation in a very short time. The system can also be extended upon request to include an additional oven module, thus doubling the throughput.
2.1019.0010
OMNIS Coulometer Module without stirrerCoulometer module without magnetic stirrer for connection to an OMNIS Titrator or to an OMNIS Coulometer as enhancement to include a measuring interface.
2.1019.0110
OMNIS Coulometer Module with stirrerCoulometer module with magnetic stirrer for connection to an OMNIS Titrator or to an OMNIS Coulometer as enhancement to include a measuring interface.
2.851.0010
851 Titrando with generator electrode with diaphragmCoulometer including generator electrode with diaphragm and 801 Magnetic Stirrer.Coulometry is the ideal method for water content determination in liquids, solids, and gases when it comes to water content determination in the trace range (10 µg to 10 mg absolute water). In addition, coulometry is an absolute method and thus no titer determination is necessary.Coulometric titrations are carried out easily and quickly with the 851 Titrando.Recommended measuring range: 10 µg - 200 mg absolute waterFor use with OMNIS Software, tiamo software, or Touch Control unit. Compliance with GMP/GLP and FDA regulations such as 21 CFR Part 11, if required
2.851.0110
851 Titrando with generator electrode without diaphragmCoulometer including generator electrode without diaphragm.Coulometry is the ideal method for water content determination in liquids, solids, and gases when it comes to water content determination in the trace range (10 µg to 10 mg absolute water). In addition, coulometry is an absolute method and thus no titer determination is necessary.Coulometric titrations are carried out easily and quickly with the 851 Titrando.Recommended measuring range: 10 µg - 200 mg absolute water.For use with OMNIS Software, tiamo software, or Touch Control unit. Compliance with GMP/GLP and FDA regulations such as 21 CFR Part 11, if required.
2.810.0010
810 Sample ProcessorSample Processor for the automated analysis of routine samples using 916 Ti-Touch or 915 KF Ti-Touch.Sample Processor with one workstation and one built-in membrane pump for the automatic processing of potentiometric as well as Karl Fischer titrations, in series with small to medium quantities. In addition to the built-in pump, an additional one (membrane or peristaltic) and up to three dosing devices for Liquid Handling tasks can be connected.Because of the multitude of application variants, rack, stirrer, titration head, Swing Head and sample vessels must be tailored to the application and ordered separately.
2.899.3110
899 Coulometer with generator electrode without diaphragm and 885 Compact Oven SCThis titration system is comprised of an 899 Coulometer and an 885 Compact Oven Sample Changer. It offers automated thermal sample preparation with subsequent water content determination in the smallest of spaces.This means that samples unsuitable for direct Karl Fischer titration can be analyzed. With the aid of tightly sealed sample vials, the samples are moved into the oven of the 885 Compact Oven Sample Changer. The sample is heated up, the water it contains is vaporized and channeled into the titration cell. The water content of the sample is then determined with the 899 Coulometer.
2.917.2010
917 Coulometer with generator electrode with diaphragm and 885 Compact Oven SCThe 917 Coulometer is a compact titrator for coulometric water determination in accordance with Karl Fischer. ''Reduced to the max'' – operating module, stirrer, and pump are integrated in the 917 Coulometer for rapid reagent replacement. This saves a great deal of space on the laboratory table.The 885 Compact Oven SC is used for automatic thermal sample preparation. The samples are heated in the oven to a temperature of up to 250 °C. This causes the water to vaporize and then be transported with a dry carrier gas into the 917 Coulometer titration cell in which the analysis takes place.
2.917.2110
917 Coulometer with generator electrode without diaphragm and 885 Compact Oven SCThe 917 Coulometer is a compact titrator for coulometric water determination in accordance with Karl Fischer. ''Reduced to the max'' – operating module, stirrer and pump are integrated in the 917 Coulometer for rapid reagent replacement. This saves a great deal of space on the laboratory table.The 885 Compact Oven SC is used for automatic thermal sample preparation. The samples are heated in the oven to a temperature of up to 250 °C. This causes the water to vaporize and then be transported with a dry carrier gas into the 917 Coulometer titration cell in which the analysis takes place.
2.852.0060
852 Titrando with Touch Control and generator electrode with diaphragmCoulometer including generator electrode with diaphragm, Touch Control, 801 Magnetic Stirrer, and complete volumetric titration cell.Coulometry is the ideal method for water content determination in liquids, solids, and gases when it comes to water content determination in the trace range (10 µg to 10 mg absolute water). In addition, coulometry is an absolute method and thus no titer determination is necessary.Recommended coulometry measuring range: 10 µg - 200 mg absolute waterThe 852 Titrando controls not only coulometric, but also volumetric Karl Fischer titration.For use with OMNIS Software, tiamo software, or Touch Control unit. Compliance with GMP/GLP and FDA regulations such as 21 CFR Part 11, if required.
2.852.0160
852 Titrando with Touch Control and generator electrode without diaphragmCoulometer including generator electrode without diaphragm, complete volumetric titration cell, and Touch Control.Coulometry is the ideal method for water content determination in liquids, solids, and gases when it comes to water content determination in the trace range (10 µg to 10 mg absolute water). In addition, coulometry is an absolute method and thus no titer determination is necessary.Recommended coulometry measuring range: 10 µg - 200 mg absolute waterThe 852 Titrando controls not only coulometric, but also volumetric Karl Fischer titration.For use with OMNIS Software, tiamo software, or Touch Control unit. Compliance with GMP/GLP and FDA regulations such as 21 CFR Part 11, if required.
A302060041C
2060 TI Ex Proof Process AnalyzerThe 2060 TI Ex Proof Process Analyzer is an intrinsically safe wet chemistry process analyzer for process monitoring in gas or dust zoned hazardous environments rated as zone 0, 1 and 2, or 20, 21, and 22. It complies with EU Directives 94/9/EC (ATEX95) and is certified for Zone 1 and Zone 2 areas. Its design combines a purge and pressurization system with intrinsically safe electronic devices. The air purging phase and permanent overpressure prevent potentially explosive atmospheres from entering the analyzer enclosure.The analyzer’s design eliminates the need for purging large analyzer shelters, allowing for direct installation at the production line within hazardous zones. It supports various kinds of techniques, including titration, Karl Fischer titration, photometry, ion-selective electrode measurements, and direct measurements.
A302060041C
2060 TI Ex Proof Process AnalyzerThe 2060 TI Ex Proof Process Analyzer is an intrinsically safe wet chemistry process analyzer for process monitoring in gas or dust zoned hazardous environments rated as zone 0, 1 and 2, or 20, 21, and 22. It complies with EU Directives 94/9/EC (ATEX95) and is certified for Zone 1 and Zone 2 areas. Its design combines a purge and pressurization system with intrinsically safe electronic devices. The air purging phase and permanent overpressure prevent potentially explosive atmospheres from entering the analyzer enclosure.The analyzer’s design eliminates the need for purging large analyzer shelters, allowing for direct installation at the production line within hazardous zones. It supports various kinds of techniques, including titration, Karl Fischer titration, photometry, ion-selective electrode measurements, and direct measurements.
A252035011C
2035 Process Analyzer - PotentiometricThe 2035 Process Analyzer for Potentiometric Titration and Ion-Selective Measurements performs analyses with dedicated electrodes and titrants. Additionally, this version of the 2035 Process Analyzer is also suitable for Ion-Selective Analysis using Metrohm high performance electrodes. This accurate standard addition technique is ideal for more difficult sample matrices.The potentiometric version of the analyzer offers the most accurate results of all measuring techniques available on the market. With far more than 1000 applications already available, titration is also one of the most used methods for analysis in almost any industry for hundreds of components varying from acid/base analysis to metal concentrations in plating baths.Titration is one of the most widespread absolute chemical methods in use today. The technique is straightforward with no need for calibration.Some titration options available for this configuration:Potentiometric titration; Colorimetric titration with Fiber Optic Technology; Moisture determination based on the Karl Fischer titration method;
ADI2045010C
ADI 2045TI Process AnalyzerThe ADI 2045TI is a wet chemical analyzer. At its core lies an industrial PC with an industry standard Communication Logic Controller. Its modular wet part gives maximum flexibility to adapt the configuration to a specific application. The burettes or pumps can be chosen for all liquid handling and selection valves implemented for multiple sample streams.Simultaneous analysis between two streams and several methods gives faster response times. The control software on top of tiamo allows the user to program different sequences of analysis and set conditions and alarms. Remote access is achieved with a standard remote desktop tool for further diagnostics.The 2045TI is offering wet chem techniques: titration, Karl Fischer titration, colorimetry, direct measurement and standard additions methods. Data from external devices such as flow, density and turbidity can be imported and processed by the analyzer to compensate for results automatically and provide added monitoring value.
A302060011C
2060 Process AnalyzerThe2060 Process Analyzer is an online wet chemistry analyzer that is suitable for countless applications. This process analyzer offers a new modularity concept consisting of a central platform, which is called a «basic cabinet».The basic cabinet consists of two parts. The upper part contains a touch screen and an industrial PC. The lower part contains the flexible wet part where the hardware for the actual analysis is housed. If the basic wet part capacity is not sufficient enough to solve an analytical challenge, then the basic cabinet can be expanded to up to four additional wet part cabinets to ensure enough space to solve even the most challenging applications. The additional cabinets can be configured in such a way that each wet part cabinet can be combined with a reagent cabinet with integrated (non-contact) level detection to increase analyzer uptime.The 2060 process analyzer offers different wet chem techniques: titration, Karl Fischer titration, photometry, direct measurement and standard additions methods.To meet all project requirements (or to meet all your needs) sample preconditioning systems can be provided to guarantee a robust analytical solution. We can provide any sample preconditioning system, such as cooling or heating, pressure reduction and degassing, filtration, and many more.
- AB-424AB-424Titer determination in volumetric Karl Fischer titration
This Application contains information regarding titer determination in Karl Fischer titration, in particular regarding the water standard suitable for a titer determination and for the correct handling of the same.Titer determination for Karl Fischer titrants is indispensable, because the titer is subject to changes caused by the humidity in the air. The frequency of the determination depends on the titrant and the tightness of the system.The titer has the unit mg/mL in Karl Fischer titration. The value calculated in a titer determination indicates how many milligrams of water react on one milliliter of titrant.
- AN-K-073Volumetric Karl Fischer titration with Scharlau Aquagent® reagents
Test measurements on water standards are performed with an OMNIS KF Titrator and Karl Fischer reagents Aquagent® Complet 5 and Methanol Fast from Scharlau.
- AB-077AB-077Volumetric water content determination according to Karl Fischer – Tips and tricks for volumetric Karl Fischer titration
This Application Bulletin gives an overview of the volumetric water content determination according to Karl Fischer. Amongst others, it describes the handling of electrodes, samples, and water standards. The described procedures and parameters comply with the ASTM E203.
- AB-142AB-142Karl Fischer water determination in gases
This Application Bulletin describes the determination of water in non-explosive and non-flammable gaseous samples using the coulometric Karl Fischer method. This method is ideal for very low water contents.
- AB-421AB-421Automated coulometric Karl Fischer titration
MATi 4 (Metrohm Automated Titration) is a configured system for automated water content determination in liquid samples using coulometric Karl Fischer titration. The maximum sample volume is 5 mL. Up to 160 samples are filled in glass vials and sealed with lids. This ensures that the water content in the samples remains constant. The samples are aspirated and transferred into the coulometric cell through a needle. The tiamo™ software controls the system.
- AN-K-074Water content in crude oil determined with Karl Fischer titration
To determine water in crude oil, ASTM D4928 recommends coulometric Karl Fischer titration with the oven method, allowing full automation for high reproducibility.
- WP-023WP-023Karl Fischer titration and near-infrared spectroscopy in perfect synergy
Metrohm has shaped moisture analysis for more than half a century. Find out about new developments in water analysis and learn how near-infrared spectroscopy in combination with Karl Fischer titration can increase your sample throughput and boost your productivity.
- 8.000.60788.000.6078Water determination in pharmaceuticals using an automated Karl Fischer Oven Technique
The poster describes the water determination in pharmaceuticals using the Karl Fischer oven technique.
- AN-K-076Vinylene carbonate water determination via coulometric Karl Fischer titration
Vinylene carbonate is a widely used lithium-ion battery electrolyte additive that requires strict moisture control to maintain battery performance and lifetime. Accurate moisture quantification was historically limited by side reactions, complicating the analysis. The introduction of alcohol-free coulometric Karl Fischer reagents now enables precise, reproducible moisture determination, facilitating more reliable control of additive and electrolyte quality during manufacturing.
- AB-417AB-417Automated volumetric Karl Fischer titration using MATi 11
MATi 11 (MATi = Metrohm Automated Titration) is a completely configured system for water content determination in solid or liquid samples using automated volumetric Karl Fischer titration. It contains a Polytron PT 1300 D for the homogenization of the samples. Up to 53 samples are analyzed directly in 120 mL titration beakers. The samples are weighed in the titration beaker and sealed with aluminum foil and a foil holder so that they neither lose nor absorb water.
- 8.000.60898.000.6089Automated sample measurement in Karl Fischer titration
This poster describes a method for automated and precise dosing of liquid samples into the Karl Fischer titration cell using Metrohm Dosino liquid handling technology. First, the titer was automatically determined with ultrapure water. The same dosing procedure proved valuable for the automated water determination in highly viscous water-glycol fluids and low-boiling organic solvents such as n-pentane. Lastly, the method copes with the labor-intensive and human error-prone suitability test stipulated in chapter 2.5.12 in the European Pharmacopoeia.
- AN-K-075Moisture analysis of rebaudioside M by Karl Fischer titration
The increasing popularity of steviol glycosides as low-calorie sweeteners requires standardized analytical methodologies for reliable quality and stability assessment. Moisture content is a critical determinant of rebaudioside M shelf life, and its quantification via oven-based sample preparation coupled with volumetric Karl Fischer titration provides a precise and reproducible approach. Integration with automated systems such as the 874 Oven Sample Processor further enhances analytical throughput and operational efficiency.
- AB-407AB-407Automated volumetric Karl Fischer titration with MATi 10
This Application Bulletin provides information regarding the MATi 10 (Metrohm Automated Titration) system. MATi 10 is a completely configured system for automatic volumetric Karl Fischer titration with which the water content in liquid and solid samples can be determined. Up to 24 samples can be analyzed directly in 75 mL titration vessels. The samples are weighed into the titration vessels and covered with an aluminum foil. This prevents falsification of the water content.
- 8.000.60798.000.6079Automated Karl Fischer titration for liquid samples using edible oils as an example
The poster describes the development of an automated Karl Fischer method for determining the water content in different edible oils.
- AB-137AB-137Coulometric water content determination according to Karl Fischer
This Application Bulletin gives an overview of the coulometric water content determination according to Karl Fischer.Amongst others, it describes the handling of electrodes, samples, and water standards. The described procedures and parameters comply with the ASTM E1064.
- 8.000.60778.000.6077Determining the water content in biodiesel by Karl Fischer titration as per EN ISO 12937
This poster describes the water determination in different biodiesel samples via direct coulometric titration, the Karl Fischer oven method and an automated KF pipetting system.
- AN-K-069AN-K-069Water in E-liquids – Fully automatic determination by volumetric Karl Fischer titration
The vaping and electronic cigarette industries are growing. The mixtures used in these products are usually called e-liquid, e-fluid, or e-juice. Toensure the quality of these e-liquids, testing the most important parameters is required. One important quality control parameter is water or moisture content.Water/moisture content determination by Karl Fischer titration (KFT) is an established and reliable procedure. Compared to other methods the advantages of KFT are its accuracy, speed, and selectivity. For high water content samples, such as e-liquids, volumetric KFT is the method of choice.In this Application Note a system for the fast and reliable determination of the water content in E-liquids is presented. This fully automated system performs the analysis including system preparation, blank, titer, and sample determination completely unattended. Hence, the workload of the operator is reduced to only weighing in the sample and placing the sealed sample vessels on the system.
- AB-434AB-434Water in lithium ion battery materials – Reliable and precise determination by Karl Fischer titration
Lithium-ion batteries must be completely free of water (concentration of H2O < 20 mg/kg), because water reacts with the conducting salt, e.g., LiPF6, to form hydrofluoric acid.The water content of several materials used in lithium ion batteries can be determined reliably and precisely by coulometric Karl-Fischer titration. In this Application Bulletin the determination for the following materials is described:raw materials for the manufacture of lithium-ion batteries (e.g., solvents for electrolytes, carbon black/graphite); electrode coating preparations (slurry) for anode and cathode coating; the coated anode and cathode foils as well as in separator foil and in the combined material; electrolytes for lithium-ion batteries;
- 8.000.60268.000.6026Determination of the water content in tablets by automated Karl Fischer titration
The water content of tablets determines the release of their active ingredients as well as their chemical, physical, microbial and shelf-life properties. Accordingly, the water content is of crucial importance and has to be accurately determined. This paper describes the straightforward determination of the water content using automated volumetric Karl Fischer titration (KFT). Tedious sample preparation steps are eliminated by using a high-frequency homogenizer that additionally serves as a stirrer. Prior to titration, the homogenizer comminutes the tablets directly in the KF solution. As the comminution process takes place directly in the hermetically sealed titration vessels, interference from atmospheric humidity does not occur. Even after 24 h in the vessels, the moisture content of four different tablet type samples was within 93…108% of the initially determined values. With a coefficient of determination of 0.99993 the KF method is highly linear for water amounts between 4 and 215 mg. For all investigated tablet types, KFT provides results that lie within the range expected by the manufacturer.
- AB-280AB-280Automatic Karl Fischer water content determination with the 874 Oven Sample Processor
Generally speaking, the gas extraction or oven method can be used for all samples which release their water when they are heated up. The oven method is indispensable in cases in which the direct volumetric or coulometric Karl Fischer titration is not possible, either because the sample contains disruptive components or because the consistency of the sample makes it very difficult or even impossible to transfer it into the titration vessel.The present Application Bulletin describes automatic water content determination with the aid of the oven technique and coulometric KF titration, using samples from the food, plastic, pharmaceutical and petrochemical industry.
- AB-209AB-209Water in insulating oils, hydrocarbons, and their products – Accurate and reliable determination by Karl Fischer titration
Only coulometric Karl Fischer titration can determine low water contents with sufficient accuracy.This Application Bulletin describes the direct determination according to ASTM D6304, ASTM E1064, ASTM D1533, ASTM D3401, ASTM D4928, EN IEC 60814, EN ISO 12937, ISO 10337, DIN 51777, and GB/T 11146. The oven technique is described according to ASTM D6304, EN IEC 60814, and DIN 51777.
- AN-K-068Water content determination and acid-base titration in parallel
The water content determination by volumetric Karl Fischer titration is one of the most important analyses worldwide. Using an OMNIS system consisting of an OMNIS Titrator and an OMNIS Sample Robot, the fully automatic analysis of water content is possible in various products and matrices. The OMNIS Sample Robot is capable of running several different titrations in parallel. In this Application Note, we present the results of a volumetric Karl Fischer titration run in parallel to an aqueous acid-base titration on the same system. The water content is not influenced by the parallel running aqueous titration, allowing the combination of potentiometric titrations and Karl Fischer titrations on the same automated system.
- AN-K-038AN-K-038Water in N-acetyl-L-cysteine
Karl Fischer titration can be used to determine the water content in N-acetyl-L-cysteine. Special solvent mixtures can be used to prevent unwanted side reactions in the Karl Fischer titration. The water content of N-acetyl-L-cysteine can thus be determined quickly and accurately, as is shown in this Application Note.
- 8.000.60628.000.6062Water determination in various plastics
The presence of excessive water in plastics adversely affects the performance of polymeric goods which is why water determination is of crucial importance. This article describes the accurate and straightforward determination of the water content using the Karl Fischer Oven Method in ten different plastic types that are not amenable to direct Karl Fischer titration. The experiments revealed that besides the determination of the oven temperature, sample preparation is one of the most important steps of the analysis, especially in case of hygroscopic plastic samples.
- AN-K-044AN-K-044Water in panthenol
The water content in panthenol is determined according to Karl Fischer.
- AN-K-040AN-K-040Water in margarine
The water content of margarine is determined according to Karl Fischer.
- AN-K-030AN-K-030Water in bismuth subnitrate (BiONO3)
The water content of bismuth subnitrate is determined according to Karl Fischer.
- AN-K-035AN-K-035Water in beta-caprolactam
The water content of beta-caprolactam is determined according to Karl Fischer.
- AN-K-036AN-K-036Water in vinyl chloride (chloroethylene)
The water content of vinyl chloride is determined according to Karl Fischer.
- AN-K-045AN-K-045Water in methylcyclohexane
The water content in methylcyclohexane is determined by coulometric Karl Fischer titration.
- AN-K-024AN-K-024Water in smoked fish (salmon, trout)
The water content of smoked salmon and smoked trout is determined according to Karl Fischer.
- 8.000.61088.000.6108Comparative Study of Moisture Analysis Techniques on Cannabis
Moisture in cannabis impacts potency and must be accurately determined. Loss on drying (LOD) is the most popular method for determining moisture in cannabis. Unfortunately, this technique is not specific to moisture and the loss of any volatile components, such as terpenes, will be incorrectly classified as moisture. Karl Fischer (KF) titration is the only chemically specific test for moisture. This poster describes the instrument used to determine moisture content by Karl Fischer titration and compares the results of this data to loss on drying.
- AN-K-022AN-K-022Water in pesticide formulations
This Application Note describes the determination of water content in pesticides using Karl Fischer titration.
- AN-K-025AN-K-025Water in potato chips
The water content of potato chips is determined according to Karl Fischer using the oven method (140 °C).
- AN-K-028AN-K-028Water in color paste
The water content of color paste is determined according to Karl Fischer.
- AN-K-021AN-K-021Water in animal fat extract
The water content of animal fat extract is determined according to Karl Fischer.
- AN-K-001AN-K-001Water in potassium chlorate (KClO3)
The water content of potassium chlorate is determined according to Karl Fischer using the oven method (300 °C).
- AN-K-034AN-K-034Water in melamine
The water content of melamine is determined according to Karl Fischer in a buffered solvent mixture at 50 °C.
- AN-K-046AN-K-046Water in calcium carbonate (chalk, lime)
The water content in Ca carbonate is determined by volumetric Karl Fischer titration.
- AN-K-043AN-K-043Water in aniline
The water content of aniline is determined according to Karl Fischer in buffered solvent.
- AN-K-037AN-K-037Water in 2-methyl-5-mercaptothiadiazole
The water content of 2-methyl-5-mercaptothiadiazole is determined according to Karl Fischer using a special solvent mixture to prevent unwanted side reactions.
- AN-K-029AN-K-029Water in spices (marjoram, nutmeg, pepper)
The water content of spices is determined according to Karl Fischer. To release the water from the cells, a high-frequency homogenizer has to be used.
- AN-K-009AN-K-009Water in explosive pellets
The water content of explosive pellets is determined according to Karl Fischer after extraction with methanol.
- AN-K-018AN-K-018Water in cyclopropyl methyl ketone
The water content of cyclopropyl methyl ketone is determined according to Karl Fischer by coulometric titration using special reagents for aldehydes and ketones.
- AN-K-019AN-K-019Water in urea
In this application note, Karl Fischer titration is used to determine the water content of urea.
- AN-K-005AN-K-005Water in ink
Determination of water content in ink is possible with Karl Fischer titration, as shown in this Application Note.
- AN-K-053AN-K-053Determination of the water content in toothpaste with MATi 10
This Application Note describes the automated determination of the water content in toothpaste using volumetric Karl Fischer titration (MATi 10).
- AN-K-011AN-K-011Water in moisturizing creams (cosmetic products)
The water content of moisturising creams is determined according to Karl Fischer. Because of their high water content, the samples are first mixed and prediluted with dry methanol.
- AN-K-042AN-K-042Water in silicone oil
The water content of silicone oil is determined according to Karl Fischer by coulometric titration.
- AN-K-031AN-K-031Water in 2-methyl-1,3-butadiene and 2,5-norbornadiene
The water content of 2-methyl-1,3-butadiene and 2,5-norbornadiene is determined according to Karl Fischer using a special solvent mixture to prevent unwanted side reactions.
- AN-K-039AN-K-039Water in penicillin-G-potassium
This application note describes the water content determination in penicillin by using volumetric Karl Fischer titration. Unwanted side reactions can be avoided by using special solvent mixtures.
- AN-K-006AN-K-006Water in ointments
The water content of ointments is determined according to Karl Fischer. Because of their high water and fat content, the samples are prediluted with a 1:1 mixture of chloroform and methanol.
- AN-K-033AN-K-033Water in piperidine and piperazine
The water content of piperidine and piperazine is determined according to Karl Fischer using a buffered solvent mixture.
- AN-K-032AN-K-032Water in acetophenone and benzophenone
The water content of acetophenone and benzophenone is determined according to Karl Fischer using special KF reagents for ketones/aldehydes to prevent unwanted side reactions.
- AN-K-051AN-K-051Determination of the water content in spirits with MATi 10
This Application Note describes the automated determination of the water content in liqueur (30% v/v) using volumetric Karl Fischer titration (MATi 10).
- AN-K-020AN-K-020Water in flour (meal)
The water content of flour is determined according to Karl Fischer. To shorten the analysis times and to obtain more precise results, the determinations are carried out at 50 °C.
- AN-K-041AN-K-041Water in liquid ammonia
Determination of the water content of liquid ammonia according to Karl Fischer after absorption of the water in ethylene glycol.
- AN-K-027AN-K-027Water in lime (CaCO3)
The water content of lime is determined according to Karl Fischer using the oven method (150 °C).
- AN-K-023AN-K-023Water in ethylene dichloride
The water content of ethylene dichloride is determined according to Karl Fischer. As the sample may contain free chlorine, which interferes with the determination, separate KF reagents have to be used.
- AN-K-026AN-K-026Water in used lubricating oil
The water content of used lubricating oil is determined according to Karl Fischer by coulometric titration. To prevent unwanted side reactions special KF reagents are used.
- AN-K-015AN-K-015Water in sweet liquorice
The water content of sweet liquorice is determined according to Karl Fischer. To dissolve the sample, a mixture of methanol and formamide is used as solvent and a high-frequency homogenizer as stirring device.
- AN-K-052AN-K-052Determination of the water content in sodium acetate with MATi 10
In this application note, Karl Fischer titration is used to determine water content in sodium acetate trihydrate. The MATi 10 allows this determination to be automated, saving users time in the laboratory.
- AN-K-008AN-K-008Water in plastic chips
The water content of plastic chips is determined according to Karl Fischer. Because of the low water content of the sample, the oven method (200 °C) and coulometric titration have to be used.
- AN-K-010AN-K-010Water in coal dust
The water content of coal dust is determined according to Karl Fischer. Because of the low water content of the voluminous sample, the oven method (nitrogen, 270 °C) and coulometric titration have to be used.
- AN-K-007AN-K-007Water in yoghurt powder
The water content of yoghurt powder is determined according to Karl Fischer. Because of the relatively high water and fat content, the sample is prediluted with a 1:1 mixture of chloroform and methanol.
- AN-K-012AN-K-012Water in turbine oil
The water content of turbine oil is determined according to Karl Fischer. Because of the low water content of the sample, coulometric titration is used.
- AN-K-014AN-K-014Water in diesel fuel and gasoline
The water content of diesel fuel and petrol (gasoline) is determined according to Karl Fischer. Because of the low water content, the determinations are carried out by coulometric titration.
- AN-K-016AN-K-016Water in lemongrass oil
The water content of lemongrass oil is determined according to Karl Fischer. To prevent unwanted side reactions, special KF reagents for aldehydes and ketones are used and the determination is carried out at 0 ... 4 °C.
- AN-K-070Water in petroleum products
Moisture in petroleum products causes several issues: corrosion and wear in pipelines and storage tanks, an increase in debris load resulting in diminished lubrication, blocked filters, or even harmful bacterial growth. As a result, increased water content can lead to infrastructure damage, higher maintenance costs, or even unwanted downtimes.Coulometric Karl Fischer titration is the method of choice for low water content in petroleum products. Using a Karl Fischer oven to vaporize the water present in the sample prior to titration not only greatly reduces matrix interferences, it can also be fully automated. This allows a reliable and cost-efficient analysis of the water content according to ASTM D6304 (Procedure B) in products such as diesel, hydraulic oil, lubricant, additive, turbine oil, and base oil.
- AN-K-002AN-K-002Water in methyl ethyl ketone peroxide (butanone peroxide)
The water content of methyl ethyl ketone peroxide is determined according to Karl Fischer using two-component reagents in order to prevent unwanted side reactions. (Separate solvent is used to ensure a high excess of sulphur dioxide and amine in the titration vessel.)
- AN-K-071Water content in flour, dough, and bread
Water content determination by volumetric Karl Fischer titration is one of the most important analyses worldwide, particularly when it comes to food quality. This parameter has a major influence on the growth of microorganisms, and thus indirectly affects the storability of the raw materials and final products. Consistent quality is only possible with precise measurements during the process. This measurement is performed with the Metrohm Eco KF Titrator for flour, dough, and baked goods.
- AN-K-013AN-K-013Water in organic peroxides
The water content of organic peroxides is determined according to Karl Fischer using two-component reagents. To prevent any unwanted side reactions, the determinations are carried out at -20 °C.
- AN-K-004AN-K-004Water in lyophilizates (e.g., vaccines in sample vials)
The water content of lyophilisates contained in vials is determined by Karl Fischer titration. Conditioned solvent (methanol) is injected into the vial to dissolve the sample and extract the water (ultrasonic bath). Afterwards the contents of the vial are transferred to the titration vessel to carry out the automatic determination.
- AN-K-003AN-K-003Water in ammonium and potassium peroxodisulfate (persulfates)
The water content of ammonium and potassium peroxodisulphate is determined according to Karl Fischer using two-component reagents. To prevent unwanted side reactions the determinations are carried out at -20 °C. Because the potassium salt is insoluble in the solvent, a high-frequency homogenizer is used to disintegrate the salt particles.
- AN-K-07234433 HYDRANAL™ NEXTGEN Coulomat AG-FI
Karl Fischer reagents contain buffer substances (usually imidazole) since the reaction constant is dependent on the pH value. A constant pH therefore ensures the most repeatable results. In 2015, imidazole was classified by European Union the as a CMR (carcinogenic, mutagenic or toxic) substance and the statement H360D was added, stating possible harm to fertility or a fetus. Meanwhile, other reagents free of imidazole are available for purchase. This Application Note summarizes test measurements with 34433 HYDRANAL™ NEXTGEN Coulomat AG-FI.
- AN-K-049AN-K-049Water in plastic pellets – Interference-free determination based on ASTM D6869
The water content, also called moisture content, of plastics is an important quality parameter, as it affects the properties and processability of some plastics. A high water content can lead to degradation of the plastic by hydrolysis or cause surface imperfections. Additionally, it can affect the physical properties of some plastics.For this analysis, the oven technique is used, as volatile compounds present in plastics will interfere, if the water content is directly determined by coulometric Karl Fischer titration. The water content determination in polycarbonate pellets, performed with the 885 Compact Oven Sample Changer and 899 Coulometer, is described in this Application Note.
- 8.000.60308.000.6030Automated water determination in chocolate
For a variety of reasons, the water content of chocolate is of crucial importance and has to be accurately determined. This poster compares an automated version of the Karl Fischer titration (KFT) using the sequential addition of various solvents with the widespread manual titration at elevated temperatures using a chloroform/methanol mixture. The water contents determined by the two procedures show excellent agreement. However, manual titration requires laborintensive sample preparation, the side reactions are difficult to quantify and hazardous halogenated solvents have to be used. In contrast, automated KFT is straightforward, uses non-hazardous solvents, allows to quantify the side reactions and is easily applicable to water determinations in sugar- and fat-containing matrices.
- AN-K-017AN-K-017Water in expandable polystyrene – Oven system with closed sample vials simplifies analysis
The presence of water in expandable polystyrene (EPS) can have a negative impact on the thermal insulation properties, as it increases thermal conductivity. If EPS is exposed to a high moisture environment, additional water may be absorbed, which can further affect thermal insulation.Direct analysis of the moisture content by Karl Fischer titration requires the water to be extracted from the EPS, which involves several time-consuming steps. Therefore, determination of the water content with an oven system is preferred. As EPS expands when heated, the use of sample boats, as required by ASTM D6869, is not possible, as the EPS will contaminate the oven system. This Application Note describes the determination of water content in EPS using an oven system with closed sample vials. A determination takes about 7 to 14 min depending on the water content of the sample and the sample size.
- WP-061WP-061Moisture in petroleum products according to ASTM D6304
Knowledge of the water content in lubricating oils, additives, and similar products is important in the manufacturing, purchase, sale, or transfer of petroleum products to help estimate their quality and performance characteristics. Monitoring the water content in such products can prevent damage to infrastructure and ensure safe operation by avoiding corrosion processes and subsequent engine wear. This White Paper explains the easy determination of moisture in petroleum samples by coulometric Karl Fischer titration according to the three procedures outlined in ASTM Method D6304. A comparison is given between the procedures to determine which is most suitable for different sample types.
- AB-141AB-141Analysis of edible fats and oils – The seven most important parameters for quality control
As the determination of the exact content of individual glycerides in fats and oils is difficult and time-consuming, several fat sum parameters or fat indices are used for the characterization and quality control of fats and oils. Fats and oils are not only essential for cooking, they are also an important ingredient in pharmaceuticals and personal care products, such as ointments and creams. Consequently, several norms and standards describe the determination of the most important quality control parameters. This Application Bulletin describes eight important analytical methods for the following fat parameters in edible oils and fats:Determination of water content in accordance with the Karl Fischer method; Oxidation stability in accordance with the Rancimat method; Iodine value; Peroxide value; Saponification value; Acid value, free fatty acids (FFA); Hydroxyl number; Traces of nickel using polarography; Special care is taken to avoid chlorinated solvents in these methods. Also, as many of the mentioned methods as possible are automated.
- AN-NIR-055AN-NIR-055Determination of water content in moisturizing skin creams using near-infrared spectroscopy
Near-infrared spectroscopy (NIRS) was used for quality control of skin creams. A model for the quantification of the water content was developed based on Karl Fischer titration (KF), enabling fast and reliable atline analysis and final product quality control.
- AN-NIR-064Quality control of ammonium nitrate
Specialty chemicals have to fulfill multiple quality requirements. One of these quality parameters, which can be found in almost all certificates of analysis and specifications, is the moisture content. The standard method for the determination of moisture content is Karl Fischer titration.This method requires reproducible sample preparation, chemicals, and waste disposal. Alternatively, near-infrared spectroscopy (NIR) can be used for the determination of moisture content. With this technique, samples can be analyzed without any preparation and without using any chemicals.
- WP-089Water content determination in ketones using Hydranal™ NEXTGEN FA reagents
With Hydranal™ NEXTGEN FA reagents, the water content in ketones can be determined quickly and reliably. Compared to other existing KF reagents for ketones on the market, the side reactions are measurably better suppressed.
- AB-358AB-358Analysis of residual moisture in a lyophilized pharmaceutical product by near-infrared spectroscopy (NIRS)
This Application Bulletin describes the method of near-infrared spectroscopy in diffuse reflection for the purpose of determining residual moisture in a lyophilized pharmaceutical product. Numerous sample vials containing freeze-dried pharmaceuticals were spiked with varying amounts of water for calibration purposes. The resulting differences in the absorption wavelengths of the OH-oscillation were correlated with the water content determined by Karl Fischer titration using the algorithm of multiple linear regression (MLR).
- AN-CIC-005AN-CIC-005Iodine in a pharmaceutical product using Combustion Ion Chromatography with Inline Matrix Elimination
The iodine content in numerous iodized X-ray contrast media (ICM) is around 50% and is determined with great accuracy using Combustion Ion Chromatography. Large quantities of H2O2 (1,000 mg/L) are required for complete absorption of the iodine. Similarly, the concentration of the internal standard should be 50 mg/L. The water content of the X-ray contrast media is determined by means of Metrohm's Karl Fischer oven method and incorporated in the final calculation.Keyword: pyrohydrolysis
- AN-NIR-078Automated moisture analysis in pharmaceutical peptides
The quantification of residual moisture in lyophilized pharmaceutical peptides is an important measure for quality control in the pharmaceutical industry. For development purposes, such measurements are necessary and routinely performed during stability studies and to optimize the freeze-drying process (lyophilization). Currently, Karl Fischer titration is widely used for moisture determination in routine analysis. However, this method is time consuming and destroys the sample during analysis. This Application Note shows that near-infrared spectroscopy (NIRS) is a fast, reagentless, non-destructive method to determine moisture content in lyophilized pharmaceutical products.
- AN-NIR-079Moisture analysis in fertilizer products
Moisture content is one of the most commonly measured properties of fertilizers. Globally, regulations for different fertilizers vary, but local legal limits ensure that the maximum amount of water must not be exceeded. Next to gravimetric methods, Karl Fischer titration is often used for accurate moisture determination.Compared to these methods, near-infrared spectroscopy (NIRS) offers unique advantages: it generates reliable results within seconds, and at the same time does not create chemical waste. This Application Note explains how NIRS can offer fast, reagent-free analysis of moisture content in various fertilizer products.
- WP-071WP-071Improving the corn to ethanol fermentation process with near-infrared spectroscopy (NIRS)
The fermentation of corn starch to produce ethanol is a complex biochemical process that requires monitoring of many different parameters (e.g., solids, pH, sugar profile, glycerol, lactic and acetic acid, and water and ethanol content). Traditional laboratory analysis using primary methods (e.g. Karl Fischer titration) takes about an hour to complete and is a limiting step for increasing plant capacity and efficiency. As a fast and non-destructive analytical technique, near-infrared spectroscopy (NIRS) can replace routine laboratory analysis, decreasing operating costs and increasing plant efficiency and capacity. This White Paper describes the capabilities of the modern analytical method near-infrared (NIR) spectroscopy for monitoring and improving the fermentation process of corn to ethanol.
- AN-K-048AN-K-048Sample preparation with the oven technique – relative blank
Large sample sizes can lead to subtraction of too high blank values. This Application Note describes the calculation of a relative blank and thus helps to improve the accuracy of the method.
- AN-K-047AN-K-047Determination of the water content in transformer oil with 885 Compact Oven Sample Changer and 899 Coulometer
This Application Note describes the determination of the water content in transformer oil using the oven technique.
- AN-K-054AN-K-054Determination of the water content in tablets
This Application Note describes the determination of the water content in tablets using automated volumetric titration including sample preparation (MATi 11).
- AN-K-050AN-K-050Determination of the water content in gelatine with the 885 Compact Oven Sample Changer and the 899 Coulometer
This Application Note describes the determination of the water content in gelatine using the oven technique.
- AN-K-067AN-K-067Determination of the bromine index of aromatic hydrocarbons by coulometric titration according to ASTM D1492
The bromine index indicates the degree of unsaturation and relies on the simple addition of bromine to the double bond of alkenes. One mole of bromine is consumed for each mol of carbon-carbon double bond. The bromine index indicates the olefin content in aromatic hydrocarbons. This Application Note describes the determination by coulometric titration according to ASTM D1492.
- WP-084WP-084Quality control of analytical parameters in battery production
Lithium-ion batteries (LIBs) are the most common rechargeable options available today. Production of LIBs needs to follow stringent quality standards.
- WP-097WP-097Why switch to OMNIS Client/Server (C/S)?
OMNIS Client/Server boosts business performance with scalable server management, cutting costs by reducing hardware, energy use, and maintenance across locations.
- AN-PAN-1047Monitoring water content in refined products inline with NIR spectroscopy
A safer way to monitor moisture content in crude distillation unit overhead fractions is with inline near-infrared spectroscopy using the 2060 The NIR-Ex Analyzer.
- AN-NIR-095Quality Control of Hand Sanitizers
This application note presents near-infrared spectroscopy (NIRS) for the rapid and reliable simultaneous quantification of ethanol, glycerol, hydrogen peroxide, and water content in hand sanitizer formulations.
- AN-PAN-1051Inline process monitoring of the moisture content in propylene oxide
This Process Application Note presents a method to closely monitor low levels of moisture in propylene oxide safely and reliably by using a single explosion-proof inline process analyzer.
- AN-NIR-119Moisture content and rheology determination of fluorinated polyolefins using NIRS
Near-infrared spectroscopy streamlines ethylene tetrafluoroethylene production by offering rapid, chemical-free analysis of melt flow rate and moisture content.
- AN-NIR-121Water content in propylene glycol monomethyl ether (PGME)
Near-infrared spectroscopy (NIRS) can determine water content in PGME (propylene glycol monomethyl ether) within seconds as shown in this Application Note.
- AN-NIR-151Moisture and protein content in corn starch with NIR spectroscopy
Corn starch serves as a gelling and thickening agent in the confectionary industry. It is also an ideal reusable molding and drying medium for starch-molded candies, where its moisture content is critical to monitor. Near-infrared spectroscopy (NIRS) provides a rapid, reagent-free method to determine moisture and protein content in corn starch. The technique is straightforward to operate and suitable for atline monitoring or routine quality control laboratories.
- AN-NIR-096Water in diesel with NIRS
This Application Note highlights near-infrared spectroscopy as a faster, cost-effective alternative to KF titration for predicting water content in diesel fuel.
- AN-NIR-115Multiparameter quality control of palm oil with NIR spectroscopy
Near-infrared spectroscopy (NIRS) quickly assesses key quality parameters in palm oil such as iodine value and fatty acid profile without sample preparation.
- AN-PAN-1060Inline process monitoring of moisture content in tetrahydrofuran
This Process Application Note presents a method to accurately monitor low levels of moisture in tetrahydrofuran (THF) in «real-time» safely, reliably, and optimally with a 2060 The NIR Analyzer from Metrohm Process Analytics. Due to the hazardous and hygroscopic nature of THF, a single explosion-proof inline process analyzer is the preferred solution for industries to reduce chemical treatment, improve product quality, and increase profits.
- AN-NIR-122Quantification of water in lactose with the OMNIS NIRS Analyzer
This Application Note shows how easy it is to determine water content in the pharmaceutical excipient lactose with reagent-free near-infrared spectroscopy.
- AN-NIR-035Quality control of polyols with NIRS
Polyols are widely used as polyurethane feedstocks, where tight quality control of parameters such as hydroxyl value, acid number, moisture, and viscosity is essential. Conventional titration methods are standardized but slow and costly due to hazardous chemicals and waste handling. Near-infrared spectroscopy (NIRS), recognized by ASTM for hydroxyl value determination, enables rapid, reagent-free, multiparameter analysis of polyols with significantly lower operating costs.
- AN-NIR-143Semola and semolina quality control using NIR spectroscopy
This Application Note demonstrates the use of NIR spectroscopy for the rapid, simultaneous determination of key quality parameters in semola and semolina flours, including protein, moisture, ash content, gluten, and water absorption. Compared with conventional reference methods, NIRS provides a faster, simpler, and highly accurate alternative with excellent precision, enabling efficient quality control and consistent production of high-quality pasta products.
- AN-NIR-041Multiparameter Quality Control of Lubricants with NIRS
For lubricant analysis, determination of the Acid Number (ASTM D664), viscosity (ASTM D445), moisture content (ASTM D6304), and color number (ASTM D1500) require the use of multiple analytical technologies and, in part, large volumes of chemicals. This application note demonstrates that the XDS RapidLiquid Analyzer operating in the visible and near-infrared spectral region (Vis-NIR) provides a fast and cost-efficient alternative for the determination of the AN, viscosity, moisture content, and color number of lubricants. With no sample preparation or chemicals needed, Vis-NIR spectroscopy allows for multi parameter analysis of lubricants in less than one minute.
- AN-NIR-060Quality Control of Polyamides
Functional group and viscosity analysis (ASTM D789) of polyamides can be a lengthy and challenging process due to the sample’s limited solubility. This application note demonstrates that the DS2500 Solid Analyzer operating in the visible and near-infrared spectral region (Vis-NIR) provides a cost-efficient and fast solution for a simultaneous determination of the intrinsic viscosity as well as the amine, carboxylic, and moisture content in polyamides. With no sample preparation or chemicals needed, Vis-NIR spectroscopy allows for the analysis of polyamides in less than a minute.
- AN-NIR-044Multiparameter Quality Control of Palm Oil with NIR Spectroscopy
Determination of key quality parameters of palm oil, namely free fatty acids (FFA), iodine value (IV), moisture content, deterioration of bleachability index (DOBI), and carotene require the use of several different analytical methods, which are laborious and can lack in accuracy. This application note demonstrates that the XDS RapidLiquid Analyzer operating in the visible and near infrared spectral region (Vis-NIR) provides a cost-efficient and fast solution for the determination of these quality control parameters in palm oil. With no sample preparation or chemicals needed, Vis-NIR spectroscopy allows for the analysis of palm oil in less than a minute and can be used by anyone.
- AN-PAN-1014Automated online determination of salt in crude oil according to ASTM D3230
Automated online analysis with the 2060 TI Ex Proof Process Analyzer facilitates constant monitoring of the crude oil desalting process according to ASTM D3230.
- AN-PAN-1055Monitoring quality parameters in standard cleaning baths
Rapid inline monitoring of the major SC1/SC2 bath constituents is possible with reagent-free near-infrared spectroscopy, e.g., the 2060 The NIR-R Analyzer.
- AN-PAN-1057Inline monitoring of fermentation processes
Many fermentation quality parameters can be monitored simultaneously directly in the tank with inline near-infrared spectroscopy, such as the 2060 The NIR Analyzer.
- AN-PAN-1053Monitoring of DOTP production via esterification with inline analysis
This Process Application Note presents a way to closely monitor multiple parameters simultaneously during the dioctyl terephthalate production process with near-infrared spectroscopy.
Karl Fischer titration
KF titrators and accessories for volumetric and coulometric water content determination in liquid, solid, or gaseous samples.
Eco Coulometer_Landing page
Economical coulometric Karl Fischer titrator for low moisture content analysis.
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Add proven Metrohm performance to your lab with Ti‑Touch titration systems. Reliable results, simplified operation, and limited‑time pricing available.
Titration
Manual and fully automated titrators, titration accessories, and titration software for potentiometric and thermometric titrations.
OMNIS platform
OMNIS lets you combine all your analyses on a universal platform with just one software to control everything. Titration, near-infrared spectroscopy, and automation on a single platform.
Metrohm Process Analyzers
Metrohm Process Analytics has a long expertise in providing solutions for process analysis, process control, and process monitoring for any requirements and in all industries.
6.06001.170
Function license KFCFunction license for coulometric Karl Fischer titration for one OMNIS Titrator
6.06001.160
Function license KFT with conditioningFunction license for volumetric Karl Fischer titration with conditioning for an OMNIS titration system.
6.06001.970
Function license CoulometerFunction license for OMNIS Coulometer, includes- Liquid Handling (LQH)- Coulometric Karl Fischer titration (KFC)- Coulometric determination of the bromine index according to ASTM D1492 (BRC)- MEAS U/T/pH/CONC
6.6063.002
tiBase multi: 5 additional licensesFive additional licenses for tiBase multi.
6.6063.003
tiBase multi: 10 additional licensesTen additional licenses for tiBase multi.
6.06003.010
OMNIS Stand-Alone licenseEnables stand-alone operation of the OMNIS software on a Windows™ computer.Features:The license already includes one OMNIS instrument license.; Must be activated via the Metrohm licensing portal.;
6.06003.012
OMNIS stand-alone license with 2 instrument licensesEnables stand-alone operation of the OMNIS Software on a Windows™ computer.Features:The license already includes two OMNIS instrument licenses.; Must be activated via the Metrohm licensing portal.;
6.06002.010
OMNIS Stand-Alone: 1 instrument license1 instrument license for operating one additional OMNIS instrument in OMNIS Stand-Alone.The following instruments are supported:OMNIS instruments; Metrohm USB devices; RS-232 instruments (e.g., balance);
6.06002.012
OMNIS Stand-Alone: 5 instrument licenses5 instrument licenses for operating 5 additional OMNIS instruments for OMNIS Stand-Alone.The following instruments are supported:OMNIS instruments; Metrohm USB devices; RS-232 instruments (e.g., balance);
6.06002.013
OMNIS Stand-Alone: 10 instrument licenses10 instrument licenses for operating 10 additional OMNIS instruments for OMNIS Stand-Alone.The following instruments are supported:OMNIS instruments; Metrohm USB devices; RS-232 instruments (e.g., balance);
6.06003.110
OMNIS Client/Server license with 1 instrument licenseEnables client/server operation of the OMNIS software.Features:The software license already contains one instrument license.; Permits operation of up to 1000 OMNIS Clients on one OMNIS Server.; Must be activated via the Metrohm licensing portal.;
6.06004.010
Software License Compliance/Regulation Stand-AloneSoftware license for the use of the compliance functions in connection with a Software Stand-Alone License.
6.06004.020
Software license 3rd Party Data Integration Stand-AloneThe software license enables data exchange between the OMNIS Software and third party software (e.g., LIMS).This software license requires a valid software license for OMNIS Stand-Alone.
6.6056.207
tiamo™ 2.X light upgrade multi: 3 LicensesAdds the functions of tiamo™ multi version to tiamo™ light.
6.6056.208
tiamo™ 2.X full upgrade multi: 3 LicensesAdds the functions of tiamo™ multi version to tiamo™ full.
6.6056.925
tiamo update 2.5 CDCD ROM and documentation for updating all tiamo™ versions to 2.5.
6.6056.021
tiamo™ 2.X multi: 1 additional licenseOptional license for tiamo™ multi. For ordering the serial number of tiamo™ multi is required!
6.6056.022
tiamo™2.X multi: 5 additional licensesOptional license for tiamo™ multi. For ordering the serial number of tiamo™ multi is required!
6.6056.023
tiamo™ 2.X multi: 10 additional licensesOptional license for tiamo™ multi. For ordering the serial number of tiamo™ multi is required!
6.6056.251
Tiamo 2.5 Light CD: 1 licensetiamo™ 2.5 Light computer program for controlling a titration system.Up to two Metrohm instruments (Titrino, Titrando, etc.) can be connected; balances and other generic (i.e. non-Metrohm) instruments can be included without limitation; Graphical method editor with numerous templates; Layout manager for individual monitor interface; Professional database with reevaluation; High-performance report generator; Data export as PDF file, CSV, SLK; No parallel titration; No data export in XML format for LIMS; Dialog languages: German, English, French, Italian, Spanish, Czech, Portuguese, Polish, Russian, Slovakian, Japanese, Chinese, Traditional Chinese;
6.6056.252
Tiamo 2.5 Full CD: 1 licenseComputer program for controlling complex titration systems.Graphical method editor with numerous templates; Layout manager for individual monitor interface; Professional database with reevaluation; Export to LIMS, NuGenesis, Cyberlab, etc.; High-performance report generator; In compliance with the directives according to FDA 21 CFR Part 11; Parallel titration; Dialog languages: German, English, French, Italian, Spanish, Portuguese, Polish, Russian, Slovakian, Czech, Japanese, Chinese and Traditional Chinese;
6.6056.253
tiamo 2.5 Multi CD: 3 licensesClient/server-compatible computer program for controlling complex titration systems.Graphical method editor with numerous templates; Layout manager for individual monitor interface; Client/server database; Professional database with reevaluation; Export to LIMS, NuGenesis, Cyberlab, etc.; High-performance report generator; In compliance with the directives according to FDA 21 CFR Part 11; Parallel titration; Dialog languages: German, English, French, Italian, Spanish, Czech, Portuguese, Polish, Russian, Slovakian, Japanese, Chinese and Traditional Chinese;
6.06002.110
OMNIS Client/Server: 1 instrument license1 instrument license for operating one additional OMNIS instrument in the OMNIS Client/Server system.The following instruments are supported:OMNIS instruments; Metrohm USB devices; RS-232 instruments (e.g. balance);
6.06002.111
OMNIS Client/Server: 5 instrument licenses5 instrument licenses for operating up to 5 OMNIS instruments in the same OMNIS Client/Server system.The following instruments are supported:OMNIS instruments; Metrohm USB instruments; RS-232 instruments (e.g., balance);
6.06002.113
OMNIS Client/Server: 10 instrument licenses10 instrument licenses for operating 10 additional OMNIS instruments in the OMNIS Client/Server system.The following instruments are supported:OMNIS instruments; Metrohm USB devices; RS-232 instruments (e.g., balance) ;
6.06002.114
OMNIS Client/Server: 25 instrument licenses25 instrument licenses for operating 25 additional OMNIS instruments in the OMNIS Client/Server system.The following instruments are supported:OMNIS instruments; Metrohm USB devices; RS-232 instruments (e.g., balance);
6.06004.011
Software License Compliance/Regulation Client/ServerSoftware license for the use of the compliance functionalities in connection with an OMNIS Client/Server Software License. The compliance functionalities are available to all OMNIS Clients.
6.06004.120
Software license 3rd Party Data Integration Client/ServerThe software license enables data exchange between the OMNIS Software and third party software (e.g., LIMS).This software license requires a valid software license for OMNIS Client/Server. This functionality is available to all OMNIS Clients.
6.0338.100
Double Pt-wire electrode for volumetryIndicator electrode used for volumetric Karl Fischer titration.
6.0341.100
Double Pt-wire electrode for coulometryIndicator electrode used for coulometric Karl Fischer titration.
6.0340.000
Double Pt-wire electrode for sample changer (fixed cable)Indicator electrode (diameter = 5.3 mm, fixed cable 2 m) used for automated Karl Fischer titration.
6.00346.100
Double Pt ring electrode for volumetryIndicator electrode for Karl Fischer titration which, thanks to its two fused platinum rings, is more robust and easier to clean than the conventional platinum pin electrode (6.0338.100).
6.0345.100
Generator electrode without diaphragmGenerator electrode without diaphragm for coulometric Karl Fischer titrations, SGJ 29/22. This generator electrode is well suited for most applications where the sample is highly soluble in alcohol.
6.00349.100
Generator electrode without diaphragmGenerator electrode without diaphragm for coulometric Karl Fischer titrations, SGJ 29/22. This generator electrode is well-suited for most applications where the sample is highly soluble in alcohol.This electrode has a cable connection angled upwards.
6.0344.100
Generator electrode with diaphragmGenerator electrode with diaphragm for coulometric Karl Fischer titrations, SGJ 29/22.This generator electrode is well suited for: samples with very low absolute water contents 50 ppm; coulometric water content determination in oil samples; applications where ketone reagents are used; applications where low-conducting reagents are used (addition of chloroform, xylene >10%);
6.00348.100
Generator electrode with diaphragmGenerator electrode with diaphragm for coulometric Karl Fischer titrations, SGJ 29/22. This electrode has a cable connection angled upwards, which simplifies cable guiding and operation when used with the OMNIS Sample Robot Oven. This generator electrode is well-suited for:Samples with very low absolute water content 50 ppm; Coulometric water content determination in oil samples; Applications where ketone reagents are used; Applications where low-conducting reagents are used (addition of chloroform, xylene >10%);
- Dec 11, 2023Karl Fischer titration: When to use volumetry or coulometry
This blog article explains the most important factors to consider in order to choose the optimal Karl Fischer titration technique: coulometry or volumetry. Coulometric Karl Fischer titration (KFC) is generally used for samples with a low moisture content between 0.001% to 1%. Volumetric Karl Fischer titration (KFT) is used for samples with higher levels of moisture between 0.1% to 100%.
- Dec 6, 2021Side reactions in Karl Fischer titration
How to recognize and avoid side reactions in Karl Fischer titration that falsify results.
- Oct 12, 2020Oven method for sample preparation in Karl Fischer titration
Water and moisture content in insoluble samples and samples that contaminate the titration cell or react with the Karl Fischer reagent on our blog.
- Apr 20, 2020Moisture Analysis – Karl Fischer Titration, NIRS, or both?
Water content, moisture analysis, and moisture quantification with Karl Fischer titration and near-infrared spectroscopy.
- May 11, 2020Titer determination in Karl Fischer titration
- Oct 11, 2021Best practice for electrodes in Karl Fischer titration
- Jul 20, 2020Frequently asked questions in Karl Fischer titration – Part 1
- Aug 17, 2020Frequently asked questions in Karl Fischer titration – Part 2
- May 23, 2022Providing the Next Level of Safety with Hydranal™ NEXTGEN Reagents and OMNIS
Safe and accurate Karl Fischer titration with Metrohm OMNIS KF titrator and Hydranal™ NEXTGEN reagents.
- Feb 8, 2021ASTM D6304: Easier determination of moisture in petroleum products
- Feb 13, 2021Chemistry of Chocolate
Components of a chocolate bar and applications for chocolate quality analysis.
- Mar 1, 2021Supercharge your battery research and production
Learn more about key analytical parameters in the production of lithium batteries and in battery research and how to determine them using Metrohm technology.
- Sep 23, 2024Quality control of cathode materials
This article highlights several key parameters crucial for Li-ion battery cathode production quality and efficient recycling and the methods to analyze them.
- Jun 28, 2021Chemistry of Fireworks
Components of fireworks, how colors are formed, and more about safety and quality control.
- Mar 23, 2026How the updated GMP regulations and EU Cyber Resilience Act will affect laboratories
Discover how the updated GMP regulations and the EU Cyber Resilience Act (CRA) will impact laboratories. Learn what changes are coming, how to prepare your equipment and software, and how Metrohm supports labs in staying compliant.
- Dec 7, 2020Introduction to Analytical Instrument Qualification – Part 1
Learn more about Analytical Instrument Qualification (AIQ) for instruments in regulated environments.
- Jan 11, 2021Introduction to Analytical Instrument Qualification – Part 2
Metrohm IQ/OQ documentation provides you with the required documentation in strict accordance to the major regulations from the USP, FDA, GAMP, and PIC/S.
- Aug 7, 2023Is having a service agreement important?
If analytical instrumentation is neglected, it may become unreliable and fall into disrepair. Non-compliance with regulatory requirements is also a concern in such situations. However, regular preventive maintenance as a part of a service agreement can help avoid these situations. Metrohm Service Agreements give you peace of mind with various maintenance plans suitable for any budget.
- Apr 6, 2021Easy moisture determination in fertilizers by near-infrared spectroscopy
- Sep 28, 2020Frequently asked questions in near-infrared spectroscopy analysis – Part 1
Learn more about the difference of IR and NIR, prediction models, norms using NIRS in regulated and non-regulated environments, and more in this FAQ blog post.
- Jan 8, 2024How to implement NIR spectroscopy in your laboratory workflow
The steps needed to implement near-infrared spectroscopy in your laboratory: creating a calibration set, creating and validating prediction models, and routine analysis.
- Apr 4, 2022Five myths about online dispersive NIR spectroscopy, FT-NIR, and FT-IR – Part 2
The benefits of near-infrared spectrometers over IR photometers in process analytical technology.
- Aug 8, 2022Near-infrared spectroscopy (NIRS): The perfect solution to monitor purity of recovered solvents
Monitoring solvent purity can be done quick and safely without any sample preparation using near-infrared spectroscopy (NIRS). Within one minute NIRS can determine the quality of recovered solvents.
- Mar 23, 2020Benefits of NIR spectroscopy: Part 3
Blog on how to implement NIR spectroscopy in your laboratory workflow.
- Apr 16, 2020What to consider when standardizing titrant
Blog about why titrant standardization is important and how to determine the titer.
- Oct 2, 2023Screening and quality control of palm oil with NIR spectroscopy
Near-infrared spectroscopy (NIRS) is an excellent fit for the analysis of several key quality parameters in crude palm oil (CPO), crude palm kernel oil (CPKO), and refined, bleached, and deodorized (RBD) palm oil. Just one NIRS instrument can measure multiple QC parameters including water (moisture) content, free fatty acids (FFA), iodine value (IV), and deterioration of bleachability index (DOBI) in a fraction of the time of other analytical techniques.
- Mar 7, 2022NIR spectroscopy: a 21 CFR Part 11 compliant tool for QC and product screening
Learn more about near-infrared spectroscopy as a 21 CFR Part 11 compliant tool to assess the quality of pharmaceuticals.
- Jan 15, 2024Pulp and paper QC and product screening with NIR spectroscopy
Paper products are primarily made from treated wood fibers processed through pulp and paper mills. This involves significant chemical use and energy consumption. Ensuring quality control throughout the production chain, from timber to the final paper product, is crucial. This blog article shows how near-infrared spectroscopy (NIRS) effectively monitors multiple key quality control parameters simultaneously during pulp and paper manufacturing.
- Jul 29, 2024Edible oil analysis: A guide for beginners
Learn what edible oils are, how they are made, how to test their quality with different analytical techniques, and about the most important analysis parameters.
- Nov 27, 2023QC and product screening of ink and paint with NIRS
Ink and paint are part of everyday life. Quality control and screening of ink and paint is important along the entire production process as well as for the final products. Manufacturers can save time and money by using near-infrared spectroscopy (NIRS) to check multiple quality parameters in raw materials and finished ink and paint products. NIRS is an environmentally friendly, cost-effective, and easy-to-use analytical technique.
- Apr 22, 2024Titration – definition and principles
Titration is one of the oldest and well-established analytical methods. This blog covers the titration principle, its process, and presents different titration types.
- May 31, 2021Validation of titration methods
Learn more about titration method validation and USP 1225.
- Jul 26, 2021NIR spectroscopy in the polymer industry: The ideal tool for QC and product screening – Part 5
Near-infrared spectroscopy for assessing the quality of polyurethanes: basics, benefits, and applications.
- Jul 5, 2021NIR spectroscopy in the polymer industry: The ideal tool for QC and product screening – Part 4
Quality control of polyamides, PA66, or Nylon 66, and polymers using near-infrared spectroscopy.
- Dec 13, 2021NIR spectroscopy in the petrochemical and refinery industry: The ASTM compliant tool for QC and product screening – Part 4
Quality control of lubricants based on mineral oils and synthetic oils according to ASTM standards using near-infrared spectroscopy.
- Mar 20, 2023Building a Smart(er) Factory by implementing Process Analytics 4.0 solutions
By implementing Industry 4.0 solutions, manufacturers can increase their efficiency, productivity, and profitability while remaining competitive and improving the customer experience. Process Analytics 4.0 focuses on the evolution of process analytics. This article covers how to successfully implement a Process Analytics 4.0 solution, including choosing the right PAT, ensuring proper sample preconditioning, and acquiring reliable data.
- Aug 9, 2021From corn to ethanol: improving the fermentation process with NIRS
Improved fermentation in bioethanol production with near-infrared spectroscopy analysis.
6.01405.010
OMNIS titration vessel lid for volumetric Karl Fischer titrationTitration vessel lid for volumetric Karl Fischer titration with an OMNIS titrator.
6.01405.050
Eco titration vessel lid for volumetric Karl Fischer titrationTitration vessel lid for volumetric Karl Fischer titration with an Eco KF titrator
6.01408.010
Set of seals for Karl Fischer titration cellComplete set of seals, suitable for 6.05609.000 and 6.05609.010.
6.5609.000
KF equipmentKarl Fischer equipment for volumetry, complete set of accessories for Karl Fischer water determination
6.2816.070
Septum piercing needleUsed with Karl Fischer ovens.
6.02711.000
Spoon for pasteSuitable for use in Karl Fischer water content determinations of pasty substances such as honey, cosmetics, greases or various dairy products.The spoon for paste facilitates the addition of viscous samples. It is handled like any other spatula and enables convenient, rapid, and loss-free addition of pastes into the Karl Fischer titration vessel.We furthermore recommend the use of a homogenizer for dissolving viscous samples quickly and completely.Compatible with 6014050X0 titration vessel lids.
6.1403.010
KF drying tube / SGJ 14 and straightUsed for Karl Fischer water determination
6.05406.000
KFC equipment for OMNIS Coulometer with generator electrode with diaphragmComplete accessory set for coulometric Karl Fischer titration.
6.05406.010
KFC equipment for OMNIS Coulometer with generator electrode without diaphragmComplete accessory set for coulometric Karl Fischer titration.
6.05609.000
KFT equipment for OMNIS TitratorComplete accessory set for volumetric Karl Fischer titration.
6.05610.050
KFT equipment for Eco KF TitratorComplete accessory set for volumetric Karl Fischer titration
6.2724.010
Dust filterDust filter for Rancimats and Karl Fischer ovens.
6.02709.010
StopperPlastic stoppers, suitable for 2.1001.4220 OMNIS Karl Fischer Titrator.
6.5610.010
KFT equipment for 810/814 Sample ProcessorKarl Fischer equipment for 810 or 814 Sample Processor.
6.01406.010
Adsorber tube with lidAdsorber tube with lid for OMNIS Karl Fischer titrator, volumetric
6.05609.010
KFT equipment for OMNIS Titrator with PolytronComplete accessory set for volumetric Karl Fischer titration with Polytron.
6.05610.060
KFT equipment for Eco KF Titrator with PolytronComplete accessory set for volumetric Karl Fischer titration with Polytron
6.01543.120
Antidiffusion tipTitration tip with antidiffusion valve, suitable for OMNIS Karl Fischer titrator.
6.1421.250
KF titration vessel with lateral opening / 50-90 mLFor Karl Fischer water determinationUsed together with spoon for solid substances 6.2702.000.
6.1821.040
Filter tubeFilter tube for 6.1608.050 Drying bottle. For Rancimats and Karl Fischer ovens.
6.05406.050
KFT equipment for OMNIS Oven ModuleComplete accessory set for volumetric Karl Fischer titrations on an OMNIS Oven Module
6.01405.040
OMNIS titration vessel lid for 601406XXX titration vessels for PolytronTitration vessel lid for volumetric Karl Fischer titration with an OMNIS titrator with Polytron.
6.2037.040
Foil holderFoil holder for 75 mL sample beaker for Karl Fischer for KF Sample Changer
6.01405.060
Eco titration vessel lid for 601406XXX titration vessels for PolytronTitration vessel lid for volumetric Karl Fischer titration with an Eco KF titrator with Polytron
6.2049.040
Needle holder with Luer lockNeedle holder (58 mm) with Luer lock for the Karl Fischer ovens 860, 874 and 885.
6.2049.050
Needle holder with Luer lockNeedle holder (73 mm) with Luer lock for the Karl Fischer ovens 860, 874 and 885.
6.2816.030
Needle with Luer connectorNeedle for filling in mercury into the Multi-Mode Electrode and for sample addition in Karl Fischer titration.
6.05406.060
KFC equipment with generator electrode with diaphragm for OMNIS Oven ModuleComplete accessory set for coulometric Karl Fischer titrations with a generator electrode with diaphragm on an OMNIS Oven Module
6.05406.070
KFC equipment with generator electrode without diaphragm for OMNIS Oven ModuleComplete accessory set for coulometric Karl Fischer titrations with a generator electrode without diaphragm on an OMNIS Oven Module
6.2811.000
Molecular sieveMolecular sieve. Bottle containing 250 g. Pore size: 0.3 nm. Without moisture indicator. For Rancimats and Karl Fischer instruments.
6.02710.000
KF Dis-Cover lid for OMNIS 75 mL sample beaker, 25 piecesLid with seals for volumetric Karl Fischer Titration in 6.01402.000 and 6.01402.003 sample beakers in the OMNIS Sample Robot Pick&Place system.
6.02710.010
KF Dis-Cover lid for OMNIS 120 mL sample beaker, 16 piecesLid with seals for volumetric Karl Fischer Titration in 6.01400.200, 6.01400.300 and 6.01400.303 sample beakers in the OMNIS Sample Robot Pick&Place system.
6.01403.020
Titration head 4xM10 for KFT (P&P)Titration head with 4 M10 openings for Karl Fischer titration in Pick&Place modules of the OMNIS Sample Robot Pick&Place with 4 M10 screw nipples and stoppers.
6.1821.070
Aspiration tip M8 with M10 screw nippleFor aspirating reagent in combination with 803 Ti Stand and volumetric Karl Fischer cell. The aspiration tip fits tubing with an M8 thread. The attached tubing nipple has an M10 thread.
6.01403.050
Titration head for KFT with reinforced tips (P&P)Titration head for Karl Fischer titration in Pick&Place modules of the OMNIS Sample Robot Pick&Place. In addition to 2 reinforced antidiffusion tips, the titration head offers an opening for using an homogenizer (Polytron 1300D) or rod stirrer.
6.2811.010
Molecular sieve (US)Molecular sieve. Bottle containing 250 g. Pore size: 0.3 nm. Without moisture indicator. For Rancimats and Karl Fischer instruments.This product is intended for all users who are US residents. The material is rated hazardous in the US in accordance with OSHA Hazard Communication Standard (29 CFR 1910.1200).
6.06001.380
Temperature gradient function licenseTemperature gradient function license for OMNIS Sample Robot Oven. This license enables the slow heating-up of an unknown sample and the determination of the optimum heating-up temperature.
- Karl Fischer Titration
Information on operation, maintenance procedures, and troubleshooting for Metrohm Karl Fischer titrators and KF equipment.
- Karl Fischer Titration
Information on operation, maintenance procedures, and troubleshooting for Metrohm Karl Fischer titrators and KF equipment.
- Karl Fischer titration
- FAQs – Karl Fischer ...FAQs – Karl Fischer Titration
- FAQs – Karl Fischer ...FAQs – Karl Fischer Titration
- Fundamentals of Karl...Fundamentals of Karl Fischer Titration
- Webinar Center
Find webinars on Karl Fischer titration, potentiometric titration, ion chromatography, near-infrared spectroscopy, pH measurement, and more.
- Electrodes
Information on the maintenance of Metrohm pH, metal, Karl Fischer, surfactant, and voltammetry and cyclic voltammetric stripping electrodes.
- Electrodes
Information on the maintenance of Metrohm pH, metal, Karl Fischer, surfactant, and voltammetry and cyclic voltammetric stripping electrodes.
- Titration Courses...Titration Courses
- KF Titration – Sampl...KF Titration – Sample processing
- KF Titration – Sampl...KF Titration – Sample processing
- Class Giveaway...Class Giveaway
- Near-infrared spectroscopy
- Process analysis
- Jan 15, 2026Metrohm receives new SelectScience® Seal of Quality awards
Metrohm has been recognized by SelectScience® with two new Seals of Quality for the OMNIS platform and 930 Compact IC Flex. This honor is based on verified customer reviews from scientists and laboratory professionals worldwide.
- Nov 19, 2025IT services you can trust
Metrohm IT Services meet the highest standards for information security. This has been officially confirmed by the certification of the Metrohm Enterprise Services Information Security Management System (ISMS) to ISO standard 27001.
- Jun 9, 2025OMNIS sets new milestones
Client/server networks for up to 1000 clients, working offline for 96 hours with automatic synchronization of your data to the server, and the possibility to use the services of Amazon and Microsoft to host OMNIS in the cloud are the most important features of the latest version of OMNIS, the analytical data management system from Metrohm.
- Apr 9, 2024OMNIS Coulometer and Sample Robot Oven
With the launch of the OMNIS Coulometer, users of OMNIS have now the complete scope of titration methods at their disposal: pH measurement, potentiometric, photometric, and thermometric titration, volumetric Karl Fischer titration, and coulometry for water determination in the trace level range.
- Jun 22, 2023Water content determination in ketones using alcohol-free reagents
Alcohol-free KF reagents allow the water content to be determined in ketones via a different pathway and stoichiometric ratio with the Bunsen reaction. Honeywell’s Hydranal™ NEXTGEN FA reagents are alcohol free and contain a stabilizer to suppress the Bunsen reaction. The end result is a quick and reliable 1:1 reaction of water and iodine with fewer side reactions than other existing KF reagents for ketones on the market.
- May 8, 2023The Karl Fischer Oven Method – Step by Step
In a free webinar on June 20, 2023, participants can learn how to determine the water content in «difficult» samples using the Karl Fischer oven method.
- Feb 21, 2023Tips and tricks for Karl Fischer water determination using the oven method
A free joint webinar with Honeywell on March 15 presents the benefits of the Karl Fischer oven method. The oven method is the solution for matrices that cannot be analyzed by direct Karl Fischer titration because they release the contained moisture only very slowly, only at high temperatures, because they are poorly soluble in KF solvents, or because they undergo side reactions with the KF reagent.
- Jan 23, 2023Metrohm launches new Eco Coulometer
Metrohm is pleased to launch the Eco Coulometer, a robust, easy to use stand-alone titrator for coulometric determination of the water content in liquid, viscous, and solid matrices.
- Oct 17, 2022OMNIS 3.0 Software released
Metrohm is pleased to release OMNIS 3.0, the latest version of the company’s software for laboratory data management. Features such as compliance with 21 FDA CFR part 11 (compliance package), client/server installation, 3rd party data integration, and long-term support (LTS) versions meet the requirements especially, in the regulated environment.
- Oct 12, 2022Making your quality control of hydraulic and lube oils more efficient
In a free webinar, Metrohm presents how combining titration and near-infrared spectroscopy can make oil condition monitoring and lubricant analysis more efficient.
- Mar 15, 2022Safer Karl Fischer titrations with CMR-free reagents and OMNIS
In a free webinar jointly presented with Honeywell on March 28, 2022 we demonstrate how a new generation of CMR-free reagents and the safety features of the OMNIS Titration platform make Karl Fischer titrations safer than ever.
- Feb 1, 2021ASTM D6304 revised – Karl Fischer oven technique approved for water content in petrochemicals
- Mar 15, 2021Battery research and production
Metrohm has compiled an overview of analytical methods and dedicated applications used to analyze crucial parameters in battery research and production.
- Aug 11, 2017Metrohm acquires majority of DropSens
- Feb 3, 2020Karl Fischer titration: how to deal with tricky matrices & time wasting routines
- Mar 23, 2020OMNIS meets Cubis® II
- 8.108.50898.108.5089Monograph: Water determination by Karl Fischer Titration
Measuring water content is an essential technique for most laboratories, on par with pH measurement, weighing, and acid-base titration. The main techniques for determining water content are drying methods (such as drying ovens or infrared balances) and the Karl Fischer (KF) titration, known for its specificity and speed. This monograph provides readers a comprehensive guide to the Karl Fischer titration method.Key points presented are:Learn about Karl Fischer reagents and the chemical reaction behind the Karl Fischer titration.; Volumetry and coulometry are the two methods used in Karl Fischer titration. Learn about their differences and when to use which method.; Side reactions can affect the accuracy of KF titrations. Learn about the different interfering substances and suitable measures to suppress the side reactions.; Sample preparation is essential for accurate water determination. Techniques presented include solvent extraction and homogenization.; Applications: KF titration is used for water determination in various samples, including raw materials, cosmetics, drugs, foodstuffs, biological samples, petrochemical products, plastics, paints, lacquers, solvents, and gaseous samples.; For a comprehensive overview of practical Karl Fischer titration knowledge, download the monograph.
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- 8.000.51618.000.5161Water determination according to Karl Fischer with MATi 4 – Complete system for fully automated, coulometric Karl Fischer titration
The present brochure contains interesting information on MATi 4. MATi 4 (MATi = Metrohm Automated Titration) is a fully automated titration system for water content determination using coulometric Karl Fischer titration. This brochure describes the advantages of MATi 4.
English
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- 8.000.51608.000.5160Brochure: Water determination according to Karl Fischer with MATi 10 – Complete system for fully automated,volumetric Karl Fischer titration
The present brochure contains interesting information on MATi 10. MATi 10 (MATi = Metrohm Automated Titration) is a fully automated complete system for water content determination using volumetric Karl Fischer titration. The advantages of the MATi 10 can be found in this brochure.
English
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- 8.000.51628.000.5162Water determination according to Karl Fischer with MATi 11 – Complete system for fully automated, volumetric Karl Fischer titration, including sample preparation
The present brochure contains information on MATi 11. MATi 11 (MATi = Metrohm Automated Titration) is a fully automated titration system for water content determination using volumetric Karl Fischer titration.This brochure describes the advantages of MATi 11.
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- 8.860.50038.860.5003Brochure: 860 KF Thermoprep - Thermal sample preparation in Karl Fischer titration
Simple, safe, precise - The KF oven method allows even for unsuitable substances to be prepared for Karl Fischer titration.
English
- 8.901.50028.901.5002Brochure: 901 Titrando - Intelligent Karl Fischer Titrator
Convincing advantages:The Magic Touch - Favorites for quick titration start; iConnect - mobile measuring input with digital data transmission; iTrodes - intelligent sensors for automatic electrode detection; Intelligent dosing elements; Karl Fischer and SET titration; Sample Processor control; Client server database with tiamoTM; Parallel titration with tiamoTM; Liquid Handling with the disposable Dosino; Fully compliant with GMP/GLP and with FDA regulations such as 21 CFR Part 11; USB interfaces for sample changer, printer, PC keyboard, barcode reader…; Wireless communication via Bluetooth for printer and balance;
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- 8.870.50028.870.5002Brochure: 870 KF Titrino plus - Karl-Fischer water determination easy, safe and precise.
The present brochure introduces the 870 KF Titrino plus. The favorably priced 870 KF Titrino plus is Metrohm’s Karl Fischer titrator for volumetric water determinations.
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- 8.109.80488.109.8048Leaflet for Karl Fischer electrodes
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- 8.000.53298.000.5329Brochure: Water content in petroleum products and additives – Oven method as per ASTM D6304 makes coulometric Karl Fischer titration easier than ever
ASTM has revised method D6304. The standard method now includes the oven method. The benefits of this method are considerable:No contamination of the KF titration cell; No matrix interferences; Less solvents needed; More reliable analysis and better reproducibility of results; Automation possible for serial, completely unattended determination of multiple samples;
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- 8.875.50058.875.5005Brochure: 875 KF Gas Analyzer – Straightforward determination of water content in liquefied and permanent gases
Accurate, reproducible results at the touch of a screen: The 875 Karl Fischer Gas Analyzer is a fully automated solution for reliable water determination in liquefied and permanent gases. Have a look at our brochure to get more information about the 875 Karl Fischer Gas Analyzer.
English
- 8.885.50018.885.5001Brochure: 885 Compact Oven Sample Changer
Affordable, automated sample preparation for Karl Fischer titration.
English
- 8.109.50288.109.5028Flyer: Double Pt ring electrode for volumetric KF titration
This flyer explains the benefits and advantages of switching to the robust Double Pt ring electrode for Karl Fischer titration.
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- 8.874.50028.874.5002Brochure: 874 USB Oven Sample Processor
Automatic thermal sample preparation for Karl Fischer titration. User benefits of the 874 USB Oven Sample Processor:The 874 USB Oven Sample Processor is simply connected to the USB port of a computer and is automatically recognized.; Use your own sample vessels. The oven and the rack can be adjusted to different sample vials.; An 800 Dosino can be connected directly to the MSB port of the 874 USB Oven Sample Processorand used with a Dosing Unit for automatic replacement of the reagent.; The optimum oven temperature for every sample can be determined with the temperature gradient.; A heated transfer tube ensures that the moisture is completely transferred to the titration cell.;
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- 8.890.50028.890.5002Brochure: 890 Titrando
With the 890 Titrando for Karl Fischer titration, Metrohm is opening up an attractive introduction into the world of Titrando for price-conscious customers. The instrument was designed for routine analysis in the titration laboratory and is addressed to all with limited budgets who expect a maximum in operating convenience, data management, automation and the traceability of analysis results.
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- 8.000.54298.000.5429Brochure: Battery research and production
This brochure covers methods ranging from latest electrochemical techniques to well established methods such as titration, Karl Fischer titration, ion chromatography, and voltammetry. The overview is structured according to specific topics defining key fields areas of application:Raw materials (e.g., impurities in lithium salts, water content, eluated anions and cations, etc.); Anode and cathode materials (e.g., water content, residual alkali, etc.); Electrolytes, additives, and solvents (e.g., electrolyte composition, diffusion coefficient, ion transfer number, etc.); Separators (Water content, MacMullin number); Finished batteries (e.g., capacity and power, cyclic performance and coulombic efficiency, etc.);
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- 8.756.50008.756.5000Brochure: 756/831 Coulometer - Water determination down to trace levels
The 756 and 831 Coulometers continue Metrohm’s established line of Karl Fischer instruments for the determination of low-level water contents. Traces right down to the lower micro range can be determined with guaranteed precision and accuracy. Main features: Standard dialogue languages: English, French, German, Spanish, Portuguese, Swedish and Italian ; Backlit screen with graphic capabilities (live curve) ; Change of KF solution at the touch of a button ; Flexible but easy to operate ; Cell with or without diaphragm ; Methods memory ; Thermal sample preparation with KF oven ; Stand-alone or software-controlled ;
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- 8.000.53258.000.5325Brochure: Water Content Analysis
Metrohm is recognized as the global market leader in the field of titration. Karl Fischer titration is one of the most widely used analytical methods for moisture analysis in routine laboratory work, and it provides precise analytical results. To increase sample throughput, productivity, and product quality, water determination can be easily implemented directly inline thanks to near-infrared spectroscopy (NIRS). The results of the laboratory analysis are used to create an accurate prediction model for the NIR spectrometer. Inline moisture analysis with NIRS analytical results are generated in near real-time every second without sampling or using chemicals.
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- 8.000.54308.000.5430Brochure: Analysis of carbon materials
The small brochure covers methods ranging from Raman spectroscopy to the latest electrochemical techniques and well-established methods such as titration, Karl Fischer titration, and ion chromatography. The overview is structured according to specific carbon materials defining key analysis parameters including relevant norms and standards:Graphene (e.g., structural properties, oxygen content (Boehm titration), electrochemical evaluation, etc.); Carbon nanotubes (e.g., disorder of crystal structure, characterization in dependence of the applied potential, etc.); Graphite (e.g., characterization, intercalation and de-intercalation of lithium, water content, etc.); Carbon black (e.g., electrochemical characterization, iodine adsorption number, water content, etc.); Hard carbon (Insertion and de-insertion of sodium ions, water content;
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