Applikationer

A new Raman system design is presented that expands the applicability of Raman to See Through diffusely scattering media such as opaque packaging materials, as well as to measure the Raman spectrum and identify thermolabile, photolabile, or heterogeneous samples.

The suitability and potential of Raman spectroscopy in forensics is widely known by forensic specialists who use it in the laboratory to identify a wide variety of compounds including explosives, drugs, paints, textile fibers and inks. However, the use of laboratory-grade Raman outside the laboratory, such as for in‐situ analysis at a crime scene, was something thought possible only in forensic‐fiction until just a few years ago. Fortunately, modern portable Raman spectrometers are commercially available, and their instrumental features are comparable to Raman lab‐ spectrometers.To prove this, some extraordinarily demanding and challenging applications, in which an in‐situ standoff identification of samples might be advisable, were tested.

Law enforcement personnel, laboratory technicians, crime scene investigators and many others face a significant challenge for identification of materials in a forensic investigation.Traditionally, technicians used multiple forms of identification in order to collect results from various forms of forensic samples. Although certain technologies are ideal for precise laboratory identification, many technologies, such as Raman spectroscopy, can be successfully used for identification of multiple forensic sample types either directly in the field or in the lab. Raman spectroscopy is classified as a Category A analytical method by the Scientific Working Group for the Analysis of Seized Drugs (SWGDRUG; Version 7.1, 2016).

At a crime scene, a police officer collects a fiber sample that may prove to be invaluable evidence in identifying a criminal or exonerating an innocent person. In recent years, Raman spectroscopy has been studied extensively for forensic fiber analysis because of the high selectivity of Raman signatures, non-destruction nature of the test, and the ability to conduct the analysis without any sample preparation. The Raman spectrum can be measured directly on fabrics or fibers mounted on glass slide with very little interference from the mounting resin or the glass.

Although the process of building, validating and using a method is well-defined through software, the robustness of the method is dependent on proper practice of sampling, validation, and method maintenance. In this document, we will detail the recommended practices for using the multivariate method with NanoRam-1064. These practices are recommended for end users who are in the pharmaceutical environment, and can expand to other industries as well. This document aims to serve as a general reference for NanoRam-1064 users who would like to build an SOP for method development, validation and implementation.

Determination of chlorine in household bleaches.

Acid throwing, a historical method for retribution against women, has become a modern threat of a different nature. Concentrated acids and other corrosive substances have emerged as modern tools of social violence. Aggressors use common plastic containers with openings that create a powerful directional spray, such as lemon juice squeeze bottles. Sulfuric and phosphoric acids were chosen for analysis here due to their highly corrosive nature- acid attacks in London most commonly use sulfuric, phosphoric, and nitric acids.2017 saw a remarkable number of acid attacks in the UK, with reported incidences averaging 2x a day. Detection and regulation of acids may contribute to prevention of this social scourge.

Identification of unknown materials in the field can be a complicated affair, especially in critical situations, where speed, safety, and ease-of-operation are essential. Mira DS, Metrohm Raman’s handheld Raman analyzer, and the intelligent Universal Attachment (iUA) give the user automated Content ID capabilities. Content ID achieves through container identification of unknown materials quickly, easily, and safely.

Signal-to-noise ratio, spectrograph design, resolution of MIRA handheld Raman analyzers.

TacticID-1064 ST is a handheld Raman device that can identify materials through paper, plastic, glass, and multilayer packaging, reducing exposure risks and eliminating the need to open containers.

Determination of chlorate, nitrate, and perchlorate in firecracker powder using anion chromatography with conductivity detection after chemical suppression.

Determination of chloride, nitrite, cyanate, azide, nitrate, chlorate, sulfate, thiocyanate, thiosulfate, and perchlorate in an extract of explosives using anion chromatography with conductivity detection after chemical suppression.

The Dose-in Gradient expands the standard IC system to a gradient system. Using isocratic elution for separating the oxyhalides and the anions containing sulfur is very time-consuming. An 800 Dosino and a T-piece are used to expand the isocratic system to a binary gradient system. This is shown in the example of the determination of the standard anions, in addition to chlorate, thiosulfate, thiocyanate, and perchlorate.

Forensic institutes examine terrorist attacks and warfare agents via trace detection analysis of the used explosives and their residuals. Of particular importance is the acquisition of «chemical fingerprints» for criminal investigation departments and governmental security agencies. Institutes for public health and environmental protection analyze such compounds that can contaminate the underlying soil and infiltrate ground water.Forensic investigation with ion chromatography (IC) using suppressed conductivity detection allows a sensitive and robust determination of anionic contaminants such as chlorate, thiosulfate, thiocyanate, and perchlorate next to the common inorganic anions over a broad concentration range.

Peroxides are often used for disinfection and water treatment purposes due to their antiseptic properties. Lower concentrations between 0.3–3% are used in households, while higher concentrations can be used for sterilization purposes. Additionally, peroxides are utilized as oxidizing and bleaching agents. Peroxides, perborates, and percarbonates can easily be determined by titration. This application note presents two titration methods for peroxide analysis: ASTM D2180 for concentrated hydrogen peroxide solutions, and a second method for trace determination of hydrogen peroxide, suitable for concentrations as low as 0.4 mg/L.

Today's Raman instrumentation is faster, more rugged, and less expensive than in the past and the advances in component miniaturization have led to the design of portable devices with extremely high performance designed for field-based investigations. This study focuses on the use of handheld Raman spectroscopy for the characterization and identification of samples encountered in various application areas related to forensic science.

Small, fast high-performance Raman spectrometers are now readily available. Three real-life Raman quantitative and semi-quantitative analysis applications are discussed. These applications showcase the versatility of Raman spectroscopy and the potential impact that it can make in various industries such as security, pharmaceutical, and plastics and polymers.

Patented STRaman technology is a new Raman technique that can identify chemical species nondestructively beneath diffusely scattering packaging material such as plastics or tablet coatings.

Allowing non-destructive chemical identification through opaque materials, award-winning STRam represents an evolution in Raman technology.

An analytic chemist in your back pocket. A forensic laboratory in a suitcase. A HazMat team in the trunk of your car. First responders need all the help they can get when faced with potentially dangerous substances. Mira DS from Metrohm Raman is a sophisticated chemical analyzer that replaces the specialist with automation. The push of a button initiates proprietary Smart Acquire routines to optimize acquisition parameters and collect the highest quality spectra. These spectra are automatically subjected to library search and Mixture Matching routines capable of identifying up to three components of a mixture. When hazardous substances are detected, the user is alerted to immediate action with color-coded warnings.

Metrohm Raman presents a unique handheld materials identification system designed to meet the needs of defense and security professionals. Meet Mira DS, the most adaptable Raman analyzer available today. Mira DS was developed directly in response to requests from first responders in the field for a small, rugged, automated materialsidentification system that ensures the safety of the user in any situation.

Detection of threatening materials requires robust and sophisticated instruments capable of safe, instantaneous field-analysis of unknowns. In an environment where there is an ever-evolving threat of explosives made from commonlyavailable chemicals, explosive libraries must be customized constantly to include newly targeted materials. Mira DS from Metrohm Raman is the perfect solution for detection of explosives in the field. This handheld Raman instrument is equipped with sophisticated analysis algorithms and a suite of safety features for first responders who need the identity of a potential hazard... NOW! Mira DS and its software can be customized to respond to emerging hazards: this note describes procedures for creating custom libraries of binary explosive precursors to be used in library comparison and mixture matching routines on Mira DS. With these tools, unknown substances can be identified with color-coded warnings for fast action in critical situations.

In this White Paper, you will learn about MIRA XTR DS – the smallest, smartest, most flexible handheld Raman system with the largest libraries available on the market! MIRA XTR DS has all the benefits of 785 nm Raman interrogation: compact size, low laser power, sample preservation, long battery lifetimes... now with fluorescence rejection. Additionally, there is improved sensitivity and resolution over 1064 nm systems. This opens up new possibilities for 785 nm Raman, including strongly colored materials, common excipients, illicit materials, and more.

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