Biogenic amines and trimethylamine N-oxide (TMAO) are indicators for the quality of grape fermentation. The consumption of amine-rich wines often leads to headaches, which is why the amine concentrations in wine must be monitored. This Application Note describes the determination of trimethylamine N-oxide, putrescine, cadaverine and histamine, in addition to various standard cations, with the aid of the Metrosep C 6 - 100/4.0 column and subsequent direct conductivity detection.


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