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News (1)2.945.0010
945 Professional Detector Vario – ConductivityIntelligent stand-alone detector equipped with a high-performance IC Conductivity Detector. For use with intelligent IC instruments or as independent conductivity detector.
2.945.0020
945 Professional Detector Vario – AmperometryIntelligent stand-alone detector equipped with the IC Amperometric Detector. Outstanding selectivity due to the four measuring modes: DC, PAD, flexIPAD, CV. The excellent signal/noise ratio and the very fast start-up guarantee the highest in measurement precision. For use with intelligent IC instruments or as independent detector.
2.945.0030
945 Professional Detector Vario – Conductivity & AmperometryIntelligent stand-alone detector equipped with the high performance IC Conductivity Detector and the IC Amperometric Detector, with the four measuring modes DC, PAD, flexIPAD and CV. For use with intelligent IC instruments or as independent detector for conductivity and amperometric detection.
2.1050.0010
OMNIS IC S ModuleThe OMNIS IC S Module is the start instrument in the OMNIS IC world and gives the entire flexibility for complete customization. It includes an OMNIS High-Pressure Pump Unit and an OMNIS Actuator Unit with a flexible choice of the injection valve, and features a transparent door for easy access.The additional 7 free units enable the creation of a fully personalized IC system. Tailored to meet individual application needs, the OMNIS IC S Module can be equipped with various units, such as the OMNIS Conductivity Detector Unit, the OMNIS MSM Unit, the OMNIS MCS Unit, the OMNIS Degasser Unit, the OMNIS Peristaltic Pump Unit, the OMNIS Column Holder Unit or the OMNIS Column Thermostat Unit, or even automatic eluent production or low-pressure gradient.A baseplate or autosampler is required, along with a Reagent Organizer or Reagent Organizer Liquid Control. For full automation, there is the free choice to add an integrated OMNIS IC Autosampler or an OMNIS IC Autosampler COOL.At any time, the OMNIS IC S Module can be upgraded with freely configurable OMNIS Extension Modules to further improve the performance, for example, with sequential suppression or Metrohm Inline Sample Preparation options.The OMNIS IC instrument is compatible with the 947 Professional UV/VIS Detector Vario and the 945 Professional Detector Vario – Amperometry, expanding the options for detection.Reach out to your local IC specialist to configure your own fully customized ion chromatograph tailored to your specific application needs.
2.1050.0020
OMNIS IC S COND/MSM/PP/CHThe OMNIS IC S COND/MSM/PP/CH is the start instrument in the OMNIS IC world with basic sample introduction and chemical suppression. It is provided as a pre-installed, ready-to-use sales version with an OMNIS High-Pressure Pump Unit, an OMNIS Actuator Unit, an OMNIS Conductivity Detector Unit, an OMNIS MSM Unit, and an OMNIS Peristaltic Pump Unit with two channels. It features a transparent door for easy access and a Reagent Organizer.It is equipped with an OMNIS Column Holder Unit with intelligent column chip technology. For sample transport and injection, a peristaltic pump and a 6/2-port valve are integrated. The 3 empty unit spaces give flexibility to upgrade the system, for example, with an OMNIS Dosing Drive Unit, an OMNIS MISP Unit, an OMNIS Degasser Unit, or an OMNIS MCS Unit for sequential suppression.The OMNIS IC instrument is foreseen to be placed on an autosampler. There is the free choice to add an integrated OMNIS IC Autosampler or an OMNIS IC Autosampler COOL for full automation; alternatively, it can be placed on a baseplate, for example, in case of a double tower solution.The OMNIS IC S COND/MSM/PP/CH can be used for applications with chemical suppression. At any time, OMNIS Extension Modules can be added to upgrade the OMNIS IC S system, for example, to improve performance with sequential suppression or Metrohm Inline Sample Preparation options.The OMNIS IC instrument is compatible with the 947 Professional UV/VIS Detector Vario, and the 945 Professional Detector Vario – Amperometry, expanding the options for detection.The OMNIS IC S COND/MSM/PP/CH is an ideal choice for applications like standard anions in simple matrices such as surface or drinking water.
2.1050.0030
OMNIS IC S COND/MSM/MCS/PP/COL/DEGThe OMNIS IC S COND/MSM/MCS/PP/COL/DEG is the start instrument in the OMNIS IC world with basic sample introduction and sequential suppression. It is provided as a pre-installed, ready-to-use sales version with an OMNIS High-Pressure Pump Unit, an OMNIS Actuator Unit, an OMNIS Conductivity Detector Unit, an OMNIS MSM Unit, an OMNIS MCS Unit, an OMNIS Degasser Unit, and an OMNIS Peristaltic Pump Unit with two channels. It features a transparent door for easy access and a Reagent Organizer.The integrated OMNIS Column Thermostat Unit 1 features a removable column tray with intelligent column chip technology and regulates the column temperature (5–80 °C, depending on ambient conditions). The column thermostat is intended for single-column use but can be upgraded to support two columns at any time. For sample transport and injection, a peristaltic pump and a 6/2-port valve are integrated.The OMNIS IC instrument is foreseen to be placed on an autosampler. There is the free choice to add an integrated OMNIS IC Autosampler or an OMNIS IC Autosampler COOL for full automation; alternatively, it can be placed on a baseplate, for example, in case of a double tower solution.The system is easily upgradable with OMNIS Extension Modules. This gives unlimited flexibility to meet future demands, such as the addition of Metrohm Inline Sample Preparation Techniques, OMNIS Dosing Drive Units for enhanced liquid handling options, or automatic eluent production.The OMNIS IC instrument is compatible with the 947 Professional UV/VIS Detector Vario, and the 945 Professional Detector Vario – Amperometry, expanding the options for detection.The OMNIS IC S COND/MSM/MCS/PP/COL/DEG can be used for applications with sequential suppression, requiring temperature-controlled column conditions such as oxyhalide analysis.
2.1051.0010
OMNIS IC M ModuleThe OMNIS IC M Module is a high-class single-channel instrument in the OMNIS IC world and gives the entire flexibility for complete customization. It includes an OMNIS High-Pressure Pump Unit, an OMNIS Actuator Unit with a flexible choice of the injection valve, an OMNIS MISP Unit, and an OMNIS Column Thermostat Unit 1 (one channel, upgradeable), and features a transparent door for easy access.The OMNIS MISP Unit offers complete flexibility to add the Metrohm Inline Sample Preparation (MISP) options, which perfectly suit the application needs, such as Ultrafiltration, Metrohm intelligent Partial Loop Injection Technique (MiPT), or can be used as a holder for a trap column. The MISP techniques improve efficiency and accuracy while reducing the number of manual steps typically involved in sample preparation.The built-in Multi Flow Monitor Unit enables smart flow monitoring for up to four channels. It detects flow trend variations, for example, induced by worn tubings or fouled filtration membranes, and can trigger software actions to minimize disturbances.The additional 8 free units enable the creation of a fully personalized IC system. Tailored to meet the individual application needs, the OMNIS IC M Module can be equipped with various units, such as the OMNIS Conductivity Detector Unit, the OMNIS MSM Unit, the OMNIS MCS Unit, the OMNIS Degasser Unit, the OMNIS Peristaltic Pump Unit, or even with automatic eluent production, low-pressure gradient, or dual-column use.A baseplate or autosampler is required, along with a Reagent Organizer or Reagent Organizer Liquid Control. For full automation, there is the free choice to add an integrated OMNIS IC Autosampler or an OMNIS IC Autosampler COOL.At any time, the OMNIS IC M Module can be upgraded with freely configurable OMNIS Extension Modules, to further improve the performance.The OMNIS IC instrument is compatible with the 947 Professional UV/VIS Detector Vario, and the 945 Professional Detector Vario – Amperometry, expanding the options for detection.Reach out to your local IC specialist to configure your own fully customized ion chromatograph tailored to your specific application needs.
2.1052.0010
OMNIS IC L ModuleThe OMNIS IC L Module is the high-class dual-channel instrument in the OMNIS IC world and gives the entire flexibility for complete customization. It is equipped with two OMNIS High-Pressure Pumps, two OMNIS Actuator Units for dual operations with the flexible choice of the injection valve, an OMNIS MISP Unit, and an OMNIS Column Thermostat Unit 2 (two channel), and features a transparent door for easy access.The OMNIS MISP Unit offers complete flexibility to add the Metrohm Inline Sample Preparation (MISP) options, which perfectly suit the application needs, such as Ultrafiltration, Metrohm intelligent Partial Loop Injection Technique (MiPT), or can be used as a holder for a trap column. The MISP techniques improve efficiency and accuracy while reducing the number of manual steps typically involved in sample preparation.The built-in Multi Flow Monitor Unit enables smart flow monitoring for up to four channels. It detects flow trend variations, for example, induced by worn tubings or fouled filtration membranes, and can trigger software actions to minimize disturbances.The additional 10 free units enable the creation of a fully personalized IC system. Tailored to meet individual application needs, the OMNIS IC L Module can be equipped with various units, such as the OMNIS Conductivity Detector Unit, the OMNIS MSM Unit, the OMNIS MCS Unit, the OMNIS Degasser Unit, the OMNIS Peristaltic Pump Unit, or the OMNIS Dosing Drive Unit.A baseplate or autosampler is required, along with a Reagent Organizer or Reagent Organizer Liquid Control. For full automation, there is the free choice to add an integrated OMNIS IC Autosampler or an OMNIS IC Autosampler COOL.At any time, the OMNIS IC L Module can be upgraded with freely configurable OMNIS Extension Modules, to further improve the performance.The OMNIS IC instrument is compatible with the 947 Professional UV/VIS Detector Vario, and the 945 Professional Detector Vario – Amperometry, expanding the options for detection.Reach out to your local IC specialist to configure your own fully customized ion chromatograph tailored to your specific application needs.
2.1052.0020
OMNIS IC L 2COND/MSM/MCS/PP/DEG/DD/ROLCThe OMNIS IC L 2COND/MSM/MCS/PP/DEG/ DD/ROLC is the high-class dual-channel instrument in the OMNIS IC world. It is provided as a pre-installed, ready-to-use sales version with two OMNIS Conductivity Detector Units, an OMNIS MSM Unit, an OMNIS MCS Unit, an OMNIS Degasser Unit, an OMNIS Peristaltic Pump Unit with two channels, and an OMNIS Dosing Drive Unit. It features a transparent door for easy access and a Reagent Organizer Liquid Control.The integrated OMNIS Column Thermostat Unit 2 features a removable column tray with intelligent column chip technology and regulates the column temperature (5–80 °C, depending on ambient conditions). For sample transport and injection, a peristaltic pump and a 7/3-port valve are integrated.For high-throughput applications, the OMNIS IC L 2COND/MSM/MCS/PP/DEG/ DD/ROLC comes with an OMNIS MISP Unit for integrated sample preparation. The OMNIS MISP Unit provides complete flexibility to add Metrohm Inline Sample Preparation (MISP) options, perfectly tailored to the application needs, such as Ultrafiltration, Metrohm intelligent Loop Technique (MiPT), or can be used as a holder for a trap column. These MISP techniques enhance efficiency and accuracy while reducing the manual steps usually involved in sample preparation.The built-in Multi Flow Monitor Unit enables smart flow monitoring for up to four channels. It detects flow trend variations, for example, induced by worn tubings or fouled filtration membranes, and can trigger software actions to minimize disturbances. The included Reagent Organizer Liquid Control functions not only as a holder for liquids and eluent bottles but also has an integrated light that illuminates the instrument's interior when at least one door is open. The integrated leak and level sensors are monitored by the OMNIS software and support automatic eluent production and liquid level control.The OMNIS IC instrument is foreseen to be placed on an autosampler. There is the free choice to add an integrated OMNIS IC Autosampler or an OMNIS IC Autosampler COOL for full automation; alternatively, it can be placed on a baseplate, for example, in case of a double tower solution.The OMNIS IC instrument is compatible with the 947 Professional UV/VIS Detector Vario and the 945 Professional Detector Vario – Amperometry, expanding the options for detection.Thanks to its upgradability, it serves as a flexible, high-throughput dual-channel device. Additional upgradeability with OMNIS Extension Modules opens the horizon to meet future demands, such as an additional channel or extended liquid handling functions.The high-class OMNIS IC L instrument is the perfect choice for high-throughput dual-channel applications, such as parallel analysis of anions and cations. Due to the integrated sample preparation, even complex matrices can be handled, while the manual workload is minimized and accuracy is increased.
2.1051.0020
OMNIS IC M COND/MSM/MCS/PP/DEG/DD/ROLCThe OMNIS IC M COND/MSM/MCS/PP/DEG/ DD/ROLC is the high-class single channel instrument in the OMNIS IC world. It is provided as a pre-installed, ready-to-use sales version with an OMNIS High-Pressure Pump Unit, an OMNIS Actuator Unit, an OMNIS Conductivity Detector Unit, an OMNIS MSM Unit, an OMNIS MCS Unit, an OMNIS Degasser Unit, an OMNIS Peristaltic Pump Unit with two channels, and OMNIS Dosing Drive Unit. It features a transparent door for easy access and a Reagent Organizer Liquid Control.The integrated OMNIS Column Thermostat Unit 1 features a removable column tray with intelligent column chip technology and regulates the column temperature (5–80 °C, depending on ambient temperature). The column thermostat is intended for single-column use, but can be upgraded to support two columns at any time. For sample transport and injection, a peristaltic pump and a 7/3-port valve are integrated.For high-throughput applications, the OMNIS IC M COND/MSM/MCS/PP/DEG/DD/ROLC comes with an OMNIS MISP Unit for integrated sample preparation. The OMNIS MISP Unit provides complete flexibility to add Metrohm Inline Sample Preparation (MISP) options, perfectly tailored to the application needs, such as Ultrafiltration, Metrohm intelligent Partial Loop Injection Technique (MiPT), or can be used as a holder for a trap column. These MISP techniques enhance efficiency and accuracy while reducing the manual steps usually involved in sample preparation.The built-in Multi Flow Monitor Unit enables smart flow monitoring for up to four channels. It detects flow trend variations, for example, induced by worn tubing or fouled filtration membranes, and can trigger software actions to minimize disturbances.The included Reagent Organizer Liquid Control functions not only as a holder for liquids and eluent bottles but also has an integrated light that illuminates the instrument's interior when at least one door is open. The integrated leak and level sensors are monitored by the OMNIS software and support automatic eluent production and liquid level control.The OMNIS IC instrument is foreseen to be placed on an autosampler. There is the free choice to add an integrated OMNIS IC Autosampler or an OMNIS IC Autosampler COOL for full automation; alternatively, it can be placed on a baseplate, for example, in case of a double tower solution.The OMNIS IC instrument is compatible with the 947 Professional UV/VIS Detector Vario and the 945 Professional Detector Vario – Amperometry, expanding the options for detection.The OMNIS IC M COND/MSM/MCS/PP/DEG/DD/ROLC serves as a flexible, high-throughput single-channel device. Additional upgradeability with OMNIS Extension Modules broadens its capabilities to meet future demands, such as dual-channel ion chromatography or extended liquid handling functions.The high-class OMNIS IC M instrument is the ideal choice for qualified or sophisticated applications requiring sequential suppression and temperature-controlled column conditions, such as oxyhalide analyses or suppressed cations analyses in various matrices. Due to integrated sample preparation, even complex matrices can be handled, while manual workload is minimized and accuracy is increased.
- AN-P-087Quality labels for novel foods
This Application Note presents an update to the standard AOAC method for total GOS determination in foodstuffs.
- AN-BAT-016EIS at different states of charge with INTELLO
This application shows how EIS, combined with INTELLO and NOVA, tracks changes in internal battery resistance across SOC levels to study performance and aging mechanisms.
- AN-C-197Potassium assay in potassium citrate and citric acid oral solution
Potassium citrate and citric acid oral solutions act as systemic alkalizers. Potassium assays, validated per USP <621> and <1225>, use IC with L76 cation-exchange columns.
- AN-C-198Calcium acetate assay in calcium acetate capsules
The assay of calcium acetate, often used as a phosphate binder for dialysis patients, can be performed with ion chromatography (IC) as per USP <621> and <1225>.
- AN-CS-021Sodium in sodium bicarbonate and sodium phosphates compounded injections
Compounded injections of sodium bicarbonate are sterile solutions for correcting metabolic acidosis and other conditions requiring systemic alkalinization. Compounded injections of sodium phosphates serve as a phosphate source to either prevent or correct hypophosphatemia in patients with restricted oral intake. Ion chromatography (IC) with suppressed conductivity detection is the standardized way to accurately quantify sodium in these solutions.
- AN-FLU-002Understanding the mechanism of a bioassay indicator by fluorescence
Alamar Blue is monitored with fluorescence spectroelectrochemistry during its irreversible reduction to resorufin and further reversible reduction to dihydroresorufin.
- AN-S-375Fluoride in sodium fluoride for pharmaceutical use
Dental care products often contain sodium fluoride as an active ingredient. Manufacturers use the United States Pharmacopeia and National Formulary (USP-NF) Monograph «Sodium Fluoride» to quantify sodium fluoride and its anionic contaminants chloride and acetate in these products. The validated USP method proposes ion chromatography (IC) with suppressed conductivity detection to carry out the fluoride assay as well as the impurity determination in a single chromatogram.
- AN-S-376Fluoride in sodium fluoride gel for pharmaceutical use
Sodium fluoride gel for pharmaceutical use needs to comply with USP requirements. The actual monograph (USP 42) uses two different methods for the identification and the assay. Ion chromatography allows the analysis of these two parameters in one single determination. In the course of the USP monograph modernization, this ion chromatographic approach makes this type of analysis even easier.
- AN-S-379Fluoride in sodium fluoride tablets for pharmaceutical use
Sodium fluoride tablets for pharmaceutical use need to comply with U.S. Pharmacopeia (USP) requirements. Ion chromatography (IC) with suppressed conductivity detection has been approved by the USP as a validated method to quantify fluoride content in sodium fluoride tablets. In the course of the USP monograph modernization, using automated IC makes this type of analysis even easier.
- AN-S-380Monofluorophosphate and fluoride in sodium monofluorophosphate for pharmaceutical use
Ion chromatography (IC) with suppressed conductivity detection has been approved by the U.S. Pharmacopeia (USP) as a validated method to quantify the monofluorophosphate (MFP) content in sodium monofluorophosphate. This Application Note shows that all acceptance criteria for the USP Monograph «Sodium Monofluorophosphate» are fulfilled and the procedure was approved as a validated USP method.
- AN-S-397IC assay for sodium chloride in sodium chloride tablets for solution
As an alternative to titration, ion chromatography (IC) with suppressed conductivity detection has been approved by USP as validated method to quantify chloride content in NaCl tablets for solution or oral use.
- AN-S-399IC assay for fluoride in sodium fluoride and acidulated phosphate topical solution
Anticavity pharmaceuticals like sodium fluoride and acidulated phosphate topical solution products require strict quality control. This Application Note outlines the fluoride IC assay as described in the USP Monograph Sodium Fluoride and Acidulated Phosphate Topical Solution.
- AN-S-403Anions in lithium-ion battery solvents
N-Methylpyrrolidone (NMP) is crucial for lithium-ion battery production. Metrohm’s intelligent Preconcentration Technique with Matrix Elimination enables µg/L-level anion analysis in NMP.
- Feb 26, 2024Ensuring and certifying quality and compliance in regulated environments
Metrohm's AOAC Installation & Operational Qualification (Q2)-certified instruments provide peace of mind by simplifying the process of meeting regulatory requirements.
- Sep 14, 2020History of Metrohm IC – Part 3
Blog post on Metrohm ion chromatography and the introduction of sequential suppression for increased sensitivity in ion chromatographic analysis.
- Nov 18, 2024Ion chromatography for the pharmaceutical industry
The principles of ion chromatography are introduced, then some applications and benefits of using IC for pharma analysis according to USP General Chapter <1065>.
- Oct 16, 2023Applying USP validated methods for separation column equivalency
The modernization of USP Monographs now permits a broader selection of separation columns for pharmaceutical analysis using ion chromatography (IC). Column equivalency studies enable the use of alternative analytical columns without needing complicated method validation procedures. This benefits pharma researchers by saving time and effort while maintaining the accuracy and reliability of analytical results in accordance with validated methods.
- May 25, 2020Photometric complexometric titration
What is photometric complexometric titration and how does it work, read our chemistry blog.
- 8.945.50018.945.5001Brochure: 945 Professional Detector Vario IC Amperometric Detector – Amperometric detection for the determination of electroactive substances
Amperometric detectors are an alternative to conductivity and UV/VIS detectors. They are used when electroactive – i.e. oxidizable or reducible – substances are to be determined. The amperometric detector exists as an embedded detector – the IC Amperometric Detector – and as a stand-alone detector – the 945 Professional Detector Vario. The present brochure describes these two instruments
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- 8.945.30048.945.3004Declaration of Conformity for 945 Professional Detector Vario
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- 8.945.80018.945.8001Manual for 29450010 Professional Detector Vario Cond
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- 8.945.80028.945.8002Manual for 29450020 Professional Detector Vario Amp
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- 8.945.80038.945.8003Manual for 29450030 Professional Detector Vario Conductivity & Amperometry
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- 8.894.50038.894.5003Brochure: 894 Professional CVS
This brochure presents the 894 Professional CVS portfolio, including automation and the viva software.
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