Benefit from more than 2,200 state-of-the-art applications, conducted with the most accurate and efficient lab technology.
Chemical production requires precise, reliable analyzers to support the many processes across the entire value chain
From base chemicals for industrial processes to specialty chemicals used in specific applications, the chemical industry is the backbone of our modern world.
Metrohm offers robust analytical instruments suitable for both laboratory and industrial process environments. Additionally, we provide expert knowledge and top-tier, on-site service to support you.
Stringent standards stipulate the quality of the final chemical products. Metrohm is involved in standards development at ASTM and ISO contributing with our application expertise.
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OMNIS NIRS: An efficiency boost for your laboratory
Download this White Paper to learn more about how the integration of NIR spectroscopy into your quality process can boost your laboratory efficiency.
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From raw material verification to process control and final product quality, our instruments – spanning the techniques of titration, ion chromatography, spectroscopy, electrochemistry, and more – help ensure compliance, reduce downtime, and optimize workflows across a wide range of chemical processes.
- AN-H-076Determination of the iodine value in fats and oils
As a key quality control parameter for fats and oils, the iodine value (IV) represents the degree of unsaturation. In this Application Note, excess Wijs reagent reacts with double bonds in the sample, and the iodine formed is quantified by thermometric back-titration with sodium thiosulfate. Thermometric endpoint titration (TET) provides a rapid, robust alternative to potentiometric methods by detecting the reaction enthalpy change without requiring sensor maintenance.
- AN-PAN-1008Online analysis of sulfuric acid in the cumene process (phenol production)
Phenol is a key chemical intermediate used to manufacture polymers, synthetic fibers, resins, detergents, herbicides, and pharmaceuticals. Most phenol production relies on the cumene hydroperoxide route, in which acid cleavage generates phenol and acetone. This Process Application Note describes the online potentiometric titration of sulfuric acid using the 2060 TI EX Proof Process Analyzer to maintain tight process control, enhance phenol quality, and reduce chemical consumption.
- AN-NIR-150Monitoring the production of stearic acid and its salts with NIR spectroscopy
Stearic acid and stearate derivatives are produced through multistep processing and require monitoring of key quality attributes, including iodine value, acid value, moisture, ash content, melting point, and granulometry. This study demonstrates that near-infrared (NIR) spectroscopy with the OMNIS NIR Analyzer enables rapid, nondestructive quantitative analysis of these parameters for both in-process and final-product samples.
- AN-K-075Moisture analysis of rebaudioside M by Karl Fischer titration
The increasing popularity of steviol glycosides as low-calorie sweeteners requires standardized analytical methodologies for reliable quality and stability assessment. Moisture content is a critical determinant of rebaudioside M shelf life, and its quantification via oven-based sample preparation coupled with volumetric Karl Fischer titration provides a precise and reproducible approach. Integration with automated systems such as the 874 Oven Sample Processor further enhances analytical throughput and operational efficiency.
- AN-K-076Vinylene carbonate water determination via coulometric Karl Fischer titration
Vinylene carbonate is a widely used lithium-ion battery electrolyte additive that requires strict moisture control to maintain battery performance and lifetime. Accurate moisture quantification was historically limited by side reactions, complicating the analysis. The introduction of alcohol-free coulometric Karl Fischer reagents now enables precise, reproducible moisture determination, facilitating more reliable control of additive and electrolyte quality during manufacturing.
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