Carbonyl test methods for alcohols

AN-V-209

2024-06

Simultaneous determination of acetaldehyde, acetone, formaldehyde, and propionaldehyde with the Multi-Mode Electrode pro

此极谱法使用多模式电极 Pro 同时检测酒精中的羰基杂质，确保了产品的高质量和稳定性。

Determination of carbonyl impurities, such as aldehydes and ketones, in alcoholic organic solvents is essential for ensuring product quality and stability.

This Application Note describes a polarographic method that employs the Multi-Mode Electrode pro for the simultaneous determination of different carbonyl compounds in alcohols. It offers a simple and sensitive tool for industries requiring rigorous alcohol quality control.

This technique involves the formation of hydrazone derivatives through the reaction of carbonyl compounds with hydrazine sulfate. Its advantage lies in its multi-analyte determination, detection of low-concentration carbonyl compounds and applicability to a broad range of alcohols, e.g., methanol or propanol, enabling precise quality assessments.

Methanol
Isopropanol

Figure 1. 884 Professional VA manual for MME

Add ultrapure water, the sample, and electrolyte solution into the measuring vessel and degas it for 5 min. Determination is carried out with the 884 Professional VA manual for MME (Figure 1) using parameters listed in Table 1. Quantification is done using two standard additions with respective standard addition solutions.

**Table 1.** Parameters
Parameter	Setting
Mode	DME
Start potential	-0.8 V
End potential	-1.6 V
Sweep rate	20 mV/s
Peak potential acetaldehyde	-1.22 V
Peak potential formaldehyde	-1.08 V
Peak potential acetone	-1.38 V
Peak potential propionaldehyde	-1.22 V