Inline sample preparation is a powerful tool to make your ion chromatography analysis more efficient. Inline Ultrafiltration is an easy add-on that works for many samples. Use it for any type of sample which contains particles, e.g., surface water, groundwater, or wastewater.

Inline Ultrafiltration by Metrohm

Ion chromatography is equipped with Inline Ultrafiltration in many different sectors to save time and money in the laboratory:

  1. Water
  2. Environmental
  3. Pharmaceutical
  4. Food/beverage
  5. Chemical

This combination increases filtration effectiveness and sample throughput. Consumables such as syringe filters are not necessary, and the workload for sample preparation in the laboratory is significantly reduced.


How often is optimal?

Customers often ask me about how often the membrane in an Ultrafiltration cell needs to be exchanged. There is no strict limit to the number of injections per membrane filter. This number strongly depends on the level of contamination of the samples.

The optimal point in time can be easily determined using our intelligent software. MagIC Net allows you to automatically integrate a check standard measurement after a certain number of samples. When the membrane filter begins to clog, the check standard data will deviate from its accepted value. MagIC Net automatically evaluates this value, and a warning message will inform you that it is time to check the system and to exchange the membrane.

Add this feature to any MagIC Net method. Define the monitoring period for the desired result.

MagIC Net – the preferred software for ion chromatography

In any case that the limit value is exceeded, a warning message will appear in the software. The data file is highlighted in red in the database, and the respective result is also displayed in red.

Ultimate flexibility for your needs

Monitoring the check standard is useful for several analytical methods. In this example, I explained how to use it to automatically control the performance of the Inline Ultrafiltration. Of course, the MagIC Net software has many more options for flexible methods with feedback. Contact your Metrohm representative if you want to learn more.

LabCast Ultrafiltration in ion chromatography

Your knowledge take-aways

Metrohm Inline Sample Preparation (MISP)


Dr. Katinka Ruth

Senior Application Specialist Ion Chromatography
Metrohm International Headquarters, Herisau, Switzerland