Bicine (2-(Bis(2-hydroxyethyl)amino)acetic acid) is a corrosive component. It has to be avoided in acidic gas sweetening solvents. These solvents are based on organic amines. Bicine is amphoteric, holding a carboxylic and an amine group. Under the applied conditions, the amine groups are at least partially protonated and therefore may be separated by cation chromatography. The detection mode is direct conductivity detection.

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