Metrohm Inline Sample Preparation (MISP) is a collection of versatile, time- and cost- effective techniques reducing manual sample preparation. This Application Note describes the combination of Inline Dilution with Inline Ultrafiltration. Samples are automatically diluted and subsequently filtered before injection. MagIC Net allows to run intelligent dilution by checking results and rediluting the sample if the result is out of the calibration range. Also the multipoint calibration is performed by automatically diluting the stock standard solution. In this way, an automatic calibration of each analyte is effectively achieved.