The short Metrosep C Supp 2 - 100/4.0 allows applying a higher eluent flow. Together with a more concentrated eluent (7.0 instead of 5.0 mmol/L nitric acid) the run time of the four cations, sodium, potassium, magnesium, and calcium can be reduced to 5 minutes. Conductivity detection after sequential suppression is applied.