Reagent-Free Moisture Analysis by Near-Infrared Spectroscopy
11/11/2015 11:00 AM - 11/11/2015 12:00 PM

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Metrohm Service
Speaker: Keith Freel, PhD – Applications Specialist, Metrohm USA

Near-infrared (NIR) analysis offers a number of advantages compared with traditional wet chemical and other instrumental analysis methods. Advantages include rapid analysis times, recovery of the intact sample and no need for sample preparation,. Furthermore, the near-infrared method offers many economic benefits because it does not use solvents or destroy samples.

(NIR) spectroscopy has been used for decades as a rapid and cost-effective tool for determining the water content in various pharmaceutical products. Use of NIR for in-line analysis achieves better process understanding to verify product quality and allow faster release for subsequent processing. Processes can be monitored for low levels of residual moisture and alcohols for better process control and end-point determination.

Key Learning Objectives:
  • Basics of near-infrared spectroscopy and steps involved in qualitative and quantitative method development
  • Implementing Near-IR for moisture analysis in lyophilized products
  • Residual moisture determination in the online drying process

Who should attend?

  • QA/QC managers from the pharma, bio-pharma and nutraceutical industries
  • Those who want to learn about near-infrared technology and applications in the pharmaceutical industry
  • Those who are currently practicing near-IR and want to enhance their application knowledge