Mannitol, rhamnose, lactulose and lactose in blood serum with pulsed amperometric detection (PAD)

The lactulose/rhamnose (L/R) intestinal permeability test is used for the diagnosis of dysfunctional intestinal permeabilities. This test comprises the determination of mannitol, rhamnose, lactose and lactulose in addition to the usual blood sugars, e.g. glucose, galactose and saccharose. This Application Note presents the analysis of a blood plasma sample enriched with the four sugars mentioned above.

Key word: leaky gut syndrome