The Hamilton PRP-X100 - 125/4.0 IC anion column is a robust separation column based on a polystyrene-divinylbenzene copolymer. It is especially suited for the separation of chloride, nitrate and sulfate without chemical suppression. Fluoride can also be determined if the cations are first removed with an H+ cartridge. The Hamilton PRP-X100 - 125/4.0 is also the separation column of choice for the determination of silicate. The column is distinguished by a very good price-performance ratio.