Monofluorophosphate is used in toothpaste to prevent dental caries. USFDA allows up to 1.5 g/kg fluoride corresponding to 11.5 g/kg sodium monofluorophosphate on over the counter (OTC) dentifices for adults and children above 6 years. Here, a toothpaste is analyzed for monofluorophosphate by ion chromatography applying conductivity detection after chemical suppression.