Nicotine in E-liquids – Reliable and affordable determination by potentiometric titration

The vaping and electronic cigarette industries are growing. The mixtures used in these products are usually called eliquid, e-fluid, or e-juice. To ensure the qualityof these e-liquids, testing the most important quality parameters is required. One important quality control parameter is nicotine content in E-liquids.

Nicotine in tobacco is usually determined by gas chromatography or liquid chromatography. Non-aqueous acid base titration is a much more affordable alternative for this determination. As e-liquids do not contain other components, which might interfere with the titration, the aqueous acid base titration presented in this Application Note can be applied for nicotine determination.

This method is an affordable and reliable way to determine the nicotine content in E-liquids and their nicotine starting material, ensuring the quality of these products.