Fluoride in sodium fluoride and phosphoric acid gel for pharmaceutical use

Sodium fluoride and phosphoric acid gel for pharmaceutical use need to comply with USP requirements. The actual monograph (USP 42) uses two different methods for the identification and the assay. Ion chromatography allows the measurement of these two parameters within a single determination. In the course of the USP monograph modernization, this ion chromatographic approach makes this type of analysis even easier.