Quantification of USP heparin units using near-infrared spectroscopy

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Heparin acts as an efficient anticoagulant and, in addition to direct injection, is also used as a lock-flush solution for rinsing catheters. Vis-NIR spectroscopy can be used to determine the strength of contaminated and purified heparin. This Application Note demonstrates that heparin strength can be determined reliably with Vis-NIR spectroscopy.