USP recommendations: Overcoming manual titration

USP has published recommendations on replacing manual titration with autotitration for a wide range of pharmaceutical assays. This project was initiated by USP in collaboration with Metrohm to respond to current requirements regarding data integrity (ALCOA) and compliance (FDA 21 CFR part 11).

This implies that in order to ensure and improve regulatory compliance, you should consider switching to autotitration.

We have compiled a White Paper to help you to transition from manual to automated titration. Click below to get your copy.

Overcoming manual titration for USP 541 compliance

Why changing to autotitration now?

  • Ensure data integrity and regulatory compliance
  • Improve result accuracy and reliability
  • Ensure method validation and enable method transfer
  • Save time and money through automation and increased lab throughput

Download the White Paper

We have compiled a comprehensive white paper and several application documents that address typical questions that arise with the change from manual to automated titration. This white paper is intended to help follow the recommendations by USP.

Download the white paper

Switching from manual to automated titraton: How to go about this?

Start the process today

Contact us now to initiate the process of updating your methods. Our product and application specialists will gladly support you, from instrument selection to application setup.

Rely on an expert partner

Metrohm looks back on decades of experience in manual and automated titration. We provide you with the fitting equipment and instruments for your application.

Ensure a long-term solution

Make sure your application and instrumentation works in the long run. For example, Metrohm offers a 3-year warranty on instruments and guarantees the availability of spare parts for 10 years.