The quality, efficacy, and shelf life of lyophilized pharmaceutical products and ingredients depends on water content. Routine Karl Fischer titration is the prescribed technique for measuring residual moisture content to monitor manufacturing, ensure samples are within specification, and optimize freeze-drying processes for lyophilized products.
Attend this webinar to hear Doug Clark, Hydranal National Technical Specialist at Honeywell, explain special techniques and reagent considerations when testing pharmaceutical samples for moisture. Lori Spafford, Titration Product Manager at Metrohm USA, will discuss how to properly use standards and unique extraction techniques to greatly improve the repeatability and accuracy of Karl Fischer titrations.
Key learning objectives:
- Understand how to apply common extraction techniques to unique pharmaceutical sample types
- Learn proper system checks for improving repeatability and accuracy of moisture titrations
- Learn special tips for better Karl Fischer titrations in pharmaceutical samples