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Applications for the pharmaceutical industry

In this section you find Metrohm application literature. Special selections are also available for the following methods:

Title and Link Literature Method
The customer application: Fully automated ultrapure water analysis at Lonza (Customer Magazine Metrohm Information 2/2006) Article (pdf) Conductivity Measurement
Water content determination in tablets – made child’s play with Titrando plus Homogenizer (Customer Magazine Metrohm Information 2/2006) Article (pdf) Karl Fischer Titration
Determination of Maltodextrin in Pharmaceutical and Food Products Reprint (pdf,
Info Center
)
Ion Chromatography
Matrix removal using inline procedures in ion chromatography Reprint (pdf,
Info Center
)
Ion Chromatography
List of IC Application Notes concerning the pharmaceutical chemistry List (pdf) Ion Chromatography
Which electrode for which application? Overview pH measurement, Titration
Pharm PAC: Know-how package for the determination of pharmaceutical ingredients using Metrohm titrators PAC (6.6042.003) Titration
Method validation and titrator qualification using the content determination of ephedrine hydrochloride Article Titration
Titrimetric determination of surfactants and pharmaceuticals Monograph (8.000.5003) Titration
Automatic Karl Fischer Water Determination in Pharmaceuticals Reprint (pdf,
Info Center
)
Karl Fischer Titration
Water determination by Karl Fischer Titration Monograph Karl Fischer Titration

The search results can be downloaded from the Info Center or ordered from your local distributor.

Application Bulletins: Pharmaceutical industry (4)

> Download of bulletins: English, French, German
Number Title Method(s)
283-E Validation of Metrohm burets A B F I L
281-E Validation of the 774 Oven Sample Processor in combination with a KF Coulometer using standard operation procedures F
277-E Validation of Metrohm ion chromatography systems using Standard Operating Procedures I
278-E Validation of the 743 Metrohm Rancimat using Standard Operating Procedures E
276-E Validation of Metrohm VA instruments using Standard Operating Procedures B
273-E Validation of Metrohm KF coulometers using Standard Operating Procedures F
272-E Validation of Metrohm conductometers E
271-E Validation of Metrohm pH meters using Standard Operating Procedures A
269-E Titrimetric/potentiometric determination of ionic surfactants by two-phase titration using the Metrosensor Surfactrodes A
268-E Potentiometric titration of surfactants and pharmaceutical compounds A
265-E Hamilton PRP-X100 IC anion column (6.1005.000) I
263-E Titrimetric determination of pharmaceutical compounds with the NIO electrode A
262-E Phenomenex Star Ion A300 IC anion column (6.1005.100) I
261-E Metrosep Anion Dual 2 IC column (6.1006.100) I
260-E Metrosep Anion Dual 1 IC glass cartridge (6.1006.020) I
257-E Metrosep Cation 1-2 IC column (6.1010.000) I
255-E Validation of Metrohm KF titrators and KF ovens according to GLP/ISO 9001 F
252-E Validation of Metrohm titrators (potentiometric) according to GLP/ISO 9001 A F
251-E Polarographic determination of cinchocaine (dibucaine) in pharmaceutical preparations B
250-E Polarographic determination of diazepam in body fluids and pharmaceutical preparations B
241-E Determination of cadmium and lead at the «Ultra Trace» graphite electrode by anodic stripping voltammetry B
238-E Check of Dosimats according to GLP/ISO A B F K
232-E Determination of the antioxidant activity according to the Rancimat method E
228-E Diazotization titrations A G
226-E Determination of arsenic by anodic stripping voltammetry at the rotating gold electrode B
224-E Polarographic determination of pyridoxine (vitamin B6) B
220-E Voltammetric determination of platinum and rhodium in the ultratrace range B
219-E Polarographic determination of riboflavin (vitamin B2) B
218-E Polarographic determination of thiamin (vitamin B1) B
215-E Polarographic determination of folic acid (vitamin B9, vitamin BC) B
213-E Polarographic determination of nicotinamide B
211-E Sample preparation for ion chromatography I
199-E Polarographic determination of sulfide and sulfite B
196-E Polarographic determination of formaldehyde B
191-E Simultaneous polarographic determination of cystine and cysteine B
188-E pH measurement technique A
181-E Potentiometric titration of aluminum and magnesium in the same solution A
131-E Voltammetric determination of aluminum B
130-E Chloride titrations with potentiometric indication A
128-E Electrochemical detection in HPLC G
126-E Polarographic determination of quinine B
125-E Simultaneous determination of calcium and magnesium in water samples and beverages and the different types of water hardness by complexometric titration with potentiometric indication A
113-E Determination of lead, cadmium and copper in foodstuffs, waste water and sewage sludge by anodic stripping voltammetry after digestion B
109-E Karl Fischer water determination with the KF drying oven F
107-E Coulometric generation of tetrabutylammonium hydroxide in isopropanol and of perchloric acid in acetonitrile or glacial acetic acid for non-aqueous titrations of acids and bases D
101-E Complexometric titrations with the Cu ISE A
100-E Bi-amperometric determination of potassium and/or ammonium G
098-E Determination of ascorbic acid (vitamin C) and its compounds B C G
097-E Voltammetric determination of tocopherols (vitamin E) in edible oils and fats B
096-E Determination of mercury by stripping voltammetry B
083-E Determination of sodium with the ion-selective electrode A
082-E Determination of fluoride with the ion-selective electrode A
077-E Water determination according to Karl Fischer F
073-E Polarographic analysis – half-wave potentials of organic substances B
068-E Potentiometric determination of carboxyl and amino end groups in polyamide fibers A
057-E Polarographic determination of nicotine B
053-E Determination of ammonium or Kjeldahl nitrogen A D
> Download of bulletins: English, French, German
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