| Anions in different organic solvents, or in H2O2
? Such samples make chromatography very difficult and
sometimes even impossible. The matrix can harm the columns
or if chromatography is possible, might lead into bad
reproducibility and wrong results. Therefore it is important
to remove the matrix prior to the analysis.
The Metrohm Inline Matrix Elimination
setup allows the analyst to remove the matrix.
- First, the sample is injected onto a preconcentration
column.
- In a second step the matrix is washed away from
the preconcentrator while the ions of interest remain.
- In a third step the ions - now matrix free - are
injected to the analytical column.
Even though dialysis is a powerful sample preparation
tool it does not stop the relatively small organic solvent
or peroxide molecules from passing the membrane. Dialysis
separates only by the size of the matrix. That is why
the matrix elimination technique has to be used.
 |
Setup |
 |
Example: Isopropanol
A: direct injection,
B: injection using Metrohm Inline Matrix
Elimination |
See instruments: Metrohm Professional IC Systems with
Matrix Elimination
> Back to
MISP Overview |
