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Metrohm Inline Sample Preparation (MISP)
in Ion Chromatography

Manual sample preparation scheme Sample preparation in IC includes all steps which a sample has to undergo before injection into the ion chromatograph. This can be as easy as a dilution step or as complex as a clean-up using several types of solid phase extraction cartridges. Anyway whatever has to be done prior to an injection is usually expensive in time and materials. And it increases analysis time.
   
MISP scheme MISP means a series of automated inline sample preparation methods especially developed for laboratory and online applications.
These methods allow to rationalize the time-consuming and cost-intensive manual sample preparation steps dramatically. A higher throughput as well as lower analysis costs are achieved.

Automated Sample Preparation Methods

Below you will find different applications of MISP. Depending on the type of sample and/or matrix you can choose out of these predefined setups. Other procedures or combination of procedures are feasible.

Metrohm INLINE ULTRAFILTRATION Manual filtration using expensive cartridges or filter caps is no longer required.
Metrohm INLINE DIALYSIS Allows the direct injection of difficult samples such as latex emulsions, fruit juices, cutting oil emulsions etc. Metrohm Inline Dialysis is more and more becoming a standard procedure for many water laboratories.
Metrohm Intelligent INLINE DILUTION You need to dilute your sample?
You do not know the required dilution factor?
No Problem for Profession IC!
Metrohm INLINE PRECONCENTRATION Determination of traces of ions – or –
One of the Sample Preparation Methods below: Preconcentration is the key.

Metrohm INLINE MATRIX ELIMINATION Ions in water-miscible solvents?
Ions in non-ionic chemicals?
Poor reproducibility?
This is the answer!
Metrohm INLINE NEUTRALIZATION Is your sample too acidic or too alkaline for direct injection? Help is at hand!
Metrohm INLINE CATION REMOVAL Removes any interfering cations from your samples.
Metrohm INLINE TRANSITION METAL REMOVAL Removes all divalent or trivalent cations without acidifying the sample solution. This procedure prevents poisoning of columns and membrane suppressors that are sensitive to transition metal ions.
Metrohm INLINE CALIBRATION  
Metrohm INLINE SPIKING  

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