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Metrohm Inline Dialysis

Ion chromatography has established itself as a standard method for the simultaneous determination of several anions or cations in water and many other matrices. However, up to now, certain samples required complicated and time-consuming preparation steps.

Metrohm Inline Dialysis now allows the use of automatic sample dialysis directly before sample injection. The only thing required is that the samples are in a liquid, nearly homogeneous form. Solids should be separated by centrifugation in advance; The sample solution is then dialysed in the dialysis cell. Thanks to the patented stopped-flow method, 100% of the sample concentration is achieved in the acceptor solution (equilibrium dialysis). The acceptor solution is then directly injected into the IC system. The dialysis of the new sample can be carried out while the chromatogram for the previous sample is being recorded. The preceding sample preparation step does therefore not delay the analysis.

In the food analysis sector the ionic contents of milk and dairy products, for example, can easily be determined. It is no longer necessary to clarify the milk by means of the Carrez precipitation to separate off the proteins. With the Metrohm Inline Dialysis even fruit juices containing fruit pulp no longer present a problem.

See examples: Application Notes (list for download, Info Center)

S-122 Determination of fluoride, glycolate, chloride and oxalate in a latex dispersion
S-127 Determination of anions in human urine
  For more examples see the pdf file (57 kB).
Dialysis step Setup

See instruments: Metrohm Professional IC Systems with Dialysis

«ProfIC 3 - Anion» - Professional IC system with inline dialysis
«ProfIC 3 - Cation» - Professional IC system with inline dialysis
«ProfIC 7 - Anion» - Professional IC system with inline dilution and dialysis
«ProfIC 7 - Cation» - Professional IC system with inline dilution and dialysis

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